Results 131 to 140 of about 92,718 (279)
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Green chemometric approach for the simultaneous estimation of bupivacaine and meloxicam
Discover ChemistryA chemometric-assisted UV–Vis spectrophotometric method was developed and validated for the simultaneous determination of bupivacaine (BUP) and meloxicam (MEL) in bulk drug substances and laboratory-synthesized mixtures.
Shantilal Padhiyar +3 more
doaj +1 more source
Talanta OpenA new spectrofluorimetric method was devised to enable the accurate and eco-friendly determination of Linagliptin (LGT), a pharmaceutical agent recognized for its anti-diabetic properties.
Mohamed A. El Hamd +6 more
doaj +1 more source
[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich +19 more
wiley +1 more source
The AnalystSchematic work flow of Ketoconazole NDSRIs determination using LC-TQ-MS/MS.
Srinivas Nakka +2 more
openaire +2 more sources
Efficacy of Inebilizumab in N‐MOmentum Trial Participants With or Without Prior Immunosuppressants
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT This post hoc analysis examined the impact of prior immunosuppressants on the long‐term efficacy and safety of inebilizumab, a cluster of differentiation 19+ B‐cell–depleting monoclonal antibody, in participants with aquaporin‐4–seropositive neuromyelitis optica spectrum disorder from the N‐MOmentum trial (NTC02200770).
Bruce A. C. Cree +9 more
wiley +1 more source
NMR-Based metabolomic studies of breast cancer [PDF]
, 2013 Breast cancer is the most frequently diagnosed form of cancer and leading cause of cancer death in females. Current screening techniques, such as mammography, are inadequate. Screening reduces the number of deaths caused by breast cancer but also results
Yabsley, Warren
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
HYDROCARBON MEASUREMENTS AND THEIR USE AS ATMOSPHERIC TRACERS [PDF]
, 2013 Non-methane hydrocarbons (NMHCs) have been measured in the boundary layer and free troposphere to investigate their behaviour under different atmospheric chemical regimes.
Punjabi, Shalini
core
New Onset of Fibromyalgia After Exposure to a Combat Environment: A Longitudinal Cohort Study
Arthritis Care &Research, EarlyView.Objective Traumatic life events are hypothesized to be triggers for the onset of fibromyalgia. Posttraumatic stress disorder (PTSD) is a common comorbidity of fibromyalgia. However, limited prospective data are available on the development of fibromyalgia after exposure to high‐magnitude stress.
Jay B. Higgs +15 more
wiley +1 more source