Results 111 to 120 of about 92,718 (279)

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

White analytical chemistry–aligned eco-friendly, stability-indicating HPLC and HPTLC methods for simultaneous estimation of efonidipine hydrochloride ethanolate and chlorthalidone

Journal of Taibah University for Science
Efonidipine hydrochloride ethanolate and chlorthalidone is used to treat hypertension. However, no stability-indicating HPLC or HPTLC method has been reported for the concurrent analysis of these FDC products.
Ashok H. Akabari, Ketan V. Shah, Jayesh Kushwaha, Jasmina Surati, Ghanshyam G. Tejani, Sarfaraz Ahmed, Seyed Jalaleddin Mousavirad   +6 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

AI-assisted novel spectral downgrade technique for smart analysis of a quinary pharmaceutical formulation

Green Analytical Chemistry
This study presents sustainable drug analysis solutions for the pharmaceutical industry through intelligent mathematical equations and AI integration, featuring the Downgrading Spectral Resolution Technique (DSRT) monitored and analyzed by AI for the ...
Thirumalai Arunagiri, Alagammai Ganesan, Kanaka Parvathi Kannaiah, Reem Hasan Obaydo, Abdulsalam Ashkar, Hemanth Kumar Chanduluru, Hayam M. Lotfy   +6 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Solution chemistry of some dicarboxylate salts of relevance to the Bayer process [PDF]

, 2001
These ions are either significant impurities in the concentrated alkaline aluminate solutions used in the Bayer process for the purification of alumina, or are useful models for degraded organic matter in industrial Bayer liquors.
Tromans, Andrew John
core   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

White analytical chemistry driven green and sensitive UV spectroscopic method for estimation of Risankizumab

International Journal of Zoology and Applied Biosciences
Risankizumab is a humanized monoclonal antibody used for the treatment of autoimmune diseases such as plaque psoriasis. A simple, sensitive and precise UV spectroscopic method was developed and validated for the quantification of Risankizumab in pharmaceutical formulations. The maximum absorbance, was obtained at 289 nm.
openaire   +1 more source

An Eco‐Friendly and Sensitive Microwave‐Aided Spectrofluorophotometric Characterization of Mirabegron‐Loaded Nanocarriers by Amalgamation of Design of Experiments and White Analytical Chemistry

Luminescence
ABSTRACTMirabegron, a drug for treatment of overactive bladder, has low water solubility and bioavailability. Researchers used quality by design to develop and characterize second‐generation lipid nanocarriers for mirabegron, aiming to provide spatially and temporally sustained drug release. Numerous analytical methodologies for assessing mirabegron in
Pintu Prajapati, Krishna Patel, Pranav Shah, Vilas Surana, Anzarul Haque, Mohd Abul Kalam, Shailesh Shah   +6 more
openaire   +4 more sources

Rapid modification of capillaries by chicken egg white and their uses for separation of proteins in capillary isoelectric focusing [PDF]

, 2003
A simple and rapid method. for modification of; capillaries with a solution of chicken egg white is developed. The modification avoids the sorption activity of proteins onto the capillary inner walls. The capillaries are stable in.
Yang, C, Zhang, WB, Zhang, YK
core