Results 101 to 110 of about 92,718 (279)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Electrochemical sensor doped with core-shell structured molecularly imprinted polymer proposed for therapeutic drug monitoring of trazodone hydrochloride

Talanta Open
Currently, the global push for eco-friendly analytical techniques has altered the priorities of analytical methodologies in accordance with their level of adherence to the principles of green analytical chemistry. Herein, sustainable, sensitive, accurate
Amr M. Mahmoud, Nariman A. El-Ragehy, Maha A. Hegazy, Samia A. Tawfik, Ghada A. Sedik   +4 more
doaj   +1 more source

Analytical Characterisation of Pigments on pre-Roman pottery by means of Spectroscopic Techniques. Part I: white coloured shards [PDF]

, 1998
This paper is part of a systematic archaeometric investigation aimed at the characterisation of the pigments and related materials (ligand, colour substrate) used in decoration of pottery excavated in the archaeological zone of Canosa (Puglia, Italy ...
ZAMBONIN P. G., DE BENEDETTO, Giuseppe, Egidio, CATALANO F., DE BENEDETTO G. E., SABBATINI, Luigia, SABBATINI L.   +5 more
core   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

A Deep Analytical Investigation of the Aroma Chemistry of Incrocio Bruni 54 and Its Differentiation from Italian White Varieties

Fermentation
Incrocio Bruni 54 is a little-known white grape variety developed in the Marche region (Italy) from a cross between Verdicchio and Sauvignon Blanc to combine aromatic freshness with structure. In light of the growing interest in minor and autochthonous cultivars, this study provides the first comprehensive chemical characterization of the aroma profile
Maurizio Piergiovanni, Martina Moretton, Domenico Masuero, Silvia Carlin   +3 more
openaire   +1 more source

Solid-state NMR characterisation of the thermal transformation of a Hungarian white illite [PDF]

, 2005
1H, 27Al, 29Si and 39K solid-state NMR are reported from a Hungarian illite 2:1 clay for samples heated up 1600 °C. This single-phase sample has a small amount of aluminium substitution in the silica layer and very low iron-content (0.4 wt%).
Carroll, Donna L., Kemp, Thomas F., Smith, Mark E., Bastow, T. J.   +3 more
core   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Use of tri-methylated-β-cyclodextrin and sub-2 μm silica particles for enantiomers separation by nano-liquid chromatography

Journal of Chromatography Open
A short capillary column packed with RP18 sub-2 µm particles was investigated for enantioseparation of selected racemic acidic compounds such as nonsteroidal anti-inflammatory drugs (carprofen, cicloprofen, fenoprofen, flurbiprofen, ibuprofen, indoprofen,
G. D’Orazio, S. Fanali
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

A study of FT-IR spectroscopy for the identification and classifcation of haematological malignancies [PDF]

, 2009
The aim of the work presented in this thesis was to explore the use of FT-IR spectroscopy, as a complementary clinical tool for haematological laboratory analysis. FT-IR spectra were measured from air-dried and frozen cell lines derived from lymphoma,
Babrah, Jaspreet
core