Results 81 to 90 of about 495,325 (290)

Characterization and digital restauration of XIV-XV centuries written parchments by means of non-destructive techniques. Three case studies [PDF]

, 2018
Parchment is the primary writing medium of the majority of documents with cultural importance. Unfortunately, this material suffers of several mechanisms of degradation that affect its chemical-physical structure and the readability of text.
Pronti, L., Perino, Michela, Cursi, M., Santarelli, M. L., Felici, A. C., Bracciale, M. P.   +5 more
core   +3 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Whiteness Evaluation for Chemical Analysis (WECA) as a Flexible Tool and Web-Based Software for Whiteness Assessment in Analytical Chemistry

Analytica
White Analytical Chemistry (WAC) provides a holistic framework for evaluating analytical methods by balancing analytical performance, environmental sustainability, and practical efficiency.
Fotouh R. Mansour, Marcello Locatelli, Reem H. Obaydo, Amir Shaaban Farag, Alaa Bedair   +4 more
doaj   +1 more source

A new function of hydrocarbons in insect communication : maternal care and offspring signalling in the European earwig [PDF]

, 2011
International ...
Kölliker, M., Mas, F., Meunier, J.
core   +3 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Toxic Baby Furniture: The Latest Case for Making Products Safe From the Start [PDF]

, 2008
Estimates indoor pollution levels of formaldehyde -- linked to increased risks of allergies, asthma, and cancer -- emitted by cribs, changing tables, and other baby furniture.
Johanna Neumann, Rachel Gibson, Travis Madsen   +2 more
core  

Chemical investigation of a biologically active schinus molle L. leaf extract [PDF]

, 2019
The pepper tree Schinus molle L. is an evergreen ornamental plant belonging to the Anacardiaceae family, native to South America and widespread throughout the world. It has biological activities and is used in folk medicine. This paper aims to contribute
Garzoli, S., Masci, V. L., Ovidi, E., Tiezzi, A., Turchetti, G., Zago, D.   +5 more
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Integrating green and white analytical principles for endocrine disruptor analysis in aqueous matrices: From routine methods to emerging technologies

Green Analytical Chemistry
The field of research and development offers promising opportunities to optimize sample preparation and analysis in the determination of endocrine disrupting chemicals.
Michelle Klein, Martin Daniel Klassen, Torsten Claus Schmidt, Jochen Tuerk   +3 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source