Results 71 to 80 of about 495,325 (290)

Electrochemistry and application of a novel monosubstituted squarate electron-transfer mediator in a glucose oxidase-doped poly(phenol) sensor [PDF]

open access: yes, 2004
Electrosynthetic poly(phenol) nanofilms were deposited in situ on platinum electrodes in the presence and absence of glucose oxidase. The synthesis charges and currents of the nonconducting polymer films were recorded at various applied potentials for ...
Hall, Lincoln A.   +6 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

A sustainable RP-HPLC method for simultaneously estimating aceclofenac, paracetamol, and serratiopeptidase with AQbD optimization

open access: yesGreen Analytical Chemistry
This study focused on developing and validating a novel method for the simultaneous estimation of aceclofenac (AFC), paracetamol (PCM), and serratiopeptidase (SPD) using reverse phase high-performance liquid chromatography (RP-HPLC).
Vineetha Rosireddy, Manikandan Krishnan
doaj   +1 more source

Roles of Interfacial Functions in Analytical Chemistry. Construction of a scanning near-field optical microscope using a white-light source.

open access: yesBUNSEKI KAGAKU, 1998
キセノンランプからの白色光を光源とし,光走査トンネル顕微鏡方式の走査型近接場光学顕微鏡(SNOM)を試作した.微小領域の透過スペクトルを得るための基礎実験として,銅フタロシアニン及び金の2種類の薄膜試料に関して透過スペクトルを得ることを試みた.SNOMで得られた透過スペクトルを市販の分光光度計による測定結果と比較したところ,銅フタロシアニンの薄膜に対しては両者のスペクトルは良く一致したが,金の薄膜の測定結果はSNOMと分光光度計とで反対の傾向を示した.両者の測定結果の違いを金の薄膜に励起される表面プラズモンによって説明した.
Satoshi TAKAHASHI   +2 more
openaire   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Systematic review of recent metrics (2020–2025) for greenness, applicability, and analytical performance with guidelines for practical use

open access: yesResults in Chemistry
In recent years, the demand for eco-friendly analytical methods with practical applicability and high analytical performance has driven the development of numerous evaluation metrics.
Samar H. Elagamy   +3 more
doaj   +1 more source

Ten principles for developing and implementing tools in the context of white analytical chemistry

open access: yesSustainable Chemistry and Pharmacy
Producción ...
De La Fuente Ballesteros, Adrián   +3 more
openaire   +2 more sources

In vitro determination of hemoglobin A1c for diabetes diagnosis and management: technology update [PDF]

open access: yes, 2014
It is fascinating to consider the analytical improvements that have occurred since glycated hemoglobin was first used in routine clinical laboratories for diabetes monitoring around 1977; at that time methods displayed poor precision, there were no ...
English, Emma   +2 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Soil, grain and water chemistry and human selenium imbalances in Enshi district, Hubei Province, China [PDF]

open access: yes, 1996
Many elements which are essential to human and other animal health in small doses can be toxic if ingested in excess. Selenium (Se), a naturally occurring metalloid element is found in all natural materials on earth including rocks, soils, waters, air,
Fordyce, F.M.   +3 more
core  

Home - About - Disclaimer - Privacy