Results 121 to 130 of about 2,895,265 (389)

Genetic, historical and breeding aspects of the occurrence of the tobiano pattern and white markings in the Polish population of Hucul horses – a review

open access: yesJournal of Applied Animal Research, 2020
In recent years, different patterns of piebald/skewbald coat colour have become popular in horses. The tobiano pattern may appear in one of three forms: minimal, classic or maximal.
Marta Pasternak   +3 more
doaj   +1 more source

Melanism as a potential thermal benefit in eastern fox squirrels (Sciurus niger) [PDF]

open access: yes, 2019
Melanistic fox squirrels (Sciurus niger) have expanded westward and increased in frequency in the Omaha, Nebraska, and Council Bluffs, Iowa, metropolitan areas.
Ciurej, Amanda K.   +3 more
core   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Letter Written by Patricia O\u27Brien Aiken to Lieutenant Albert Shelton Aiken postmarked May 18, 1943 [PDF]

open access: yes, 1943
Hi Honey-bun – Guess who I got a letter from today—Mary Ellen—and written in her own hand writing! Can you imagine it? Or do you recall just how crooked and helpless her hands were when we were home.
Aiken, Patricia O\u27Brien
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Patients’ perception on the professional image in medical care: reflections for medical education [PDF]

open access: yesRevista Brasileira de Educação Médica
Introduction: Brazilian studies on non-verbal communication and its possible impact on the relationship between health professionals and patients are still incipient in the scientific literature.
Juliane Toffoli da Silva   +3 more
doaj   +1 more source

Method for applying photographic resists to otherwise incompatible substrates [PDF]

open access: yes, 1981
A method for applying photographic resists to otherwise incompatible substrates, such as a baking enamel paint surface, is described wherein the uncured enamel paint surface is coated with a non-curing lacquer which is, in turn, coated with a partially ...
Fuhr, W.
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

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