Results 131 to 140 of about 2,895,265 (389)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Column: Hypertension Nursing - White coat hypertension

open access: yesOnline Brazilian Journal of Nursing, 2006
White coat hypertension is defined by hypertensive blood pressure in the office, whereas blood pressure in other situations is normal, for example in ambulatory blood pressure monitoring or home blood pressure measurement.
Angela Maria Geraldo Pierin
doaj  

When the White Coat Becomes the White Cassock

open access: green, 2023
Sotirios Apostolakis, Apollonia Lazou
openalex   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

Total phenol content in seed coat of three cultivars of Phaseolus vulgaris L.

open access: yesBiotecnología Vegetal, 2016
The colors of the common bean (Phaseolus vulgaris L.) are related to some of their properties. The objective of this work was to determine the total phenol content in the seed coat of three different bean cultivars. Seeds of the cultivars 'Delicias 364' (
Yenisey Gutierrez Sánchez   +7 more
doaj  

Differential Expression of Hypertension-Associated MicroRNAs in the Plasma of Patients With White Coat Hypertension

open access: yesMedicine, 2015
White coat hypertension (WCH) is a high cardiovascular risk condition, and a fundamental understanding of the cause and pathophysiology of the disorder is still lacking.
M. Cengiz   +8 more
semanticscholar   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

White coat hypertension: improving the patient–health care practitioner relationship

open access: yesPsychology Research and Behavior Management, 2015
Briana Cobos, Kelly Haskard-Zolnierek, Krista Howard Department of Psychology, Texas State University, San Marcos, TX, USA Abstract: White coat hypertension is characterized by the variability of a patient's blood pressure measurements between the ...
Cobos B, Haskard-Zolnierek K, Howard K
doaj  

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