Results 131 to 140 of about 2,895,265 (389)
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Column: Hypertension Nursing - White coat hypertension
White coat hypertension is defined by hypertensive blood pressure in the office, whereas blood pressure in other situations is normal, for example in ambulatory blood pressure monitoring or home blood pressure measurement.
Angela Maria Geraldo Pierin
doaj
When the White Coat Becomes the White Cassock
Sotirios Apostolakis, Apollonia Lazou
openalex +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
Total phenol content in seed coat of three cultivars of Phaseolus vulgaris L.
The colors of the common bean (Phaseolus vulgaris L.) are related to some of their properties. The objective of this work was to determine the total phenol content in the seed coat of three different bean cultivars. Seeds of the cultivars 'Delicias 364' (
Yenisey Gutierrez Sánchez +7 more
doaj
Follow-up clinic and ambulatory blood pressure in normotensives and treated and untreated white coat hypertensives (evaluation after 4?9 years) [PDF]
Jorge Polónia
openalex +1 more source
White coat hypertension (WCH) is a high cardiovascular risk condition, and a fundamental understanding of the cause and pathophysiology of the disorder is still lacking.
M. Cengiz +8 more
semanticscholar +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
White coat hypertension: improving the patient–health care practitioner relationship
Briana Cobos, Kelly Haskard-Zolnierek, Krista Howard Department of Psychology, Texas State University, San Marcos, TX, USA Abstract: White coat hypertension is characterized by the variability of a patient's blood pressure measurements between the ...
Cobos B, Haskard-Zolnierek K, Howard K
doaj

