Results 131 to 140 of about 2,888,794 (390)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Column: Hypertension Nursing - White coat hypertension

open access: yesOnline Brazilian Journal of Nursing, 2006
White coat hypertension is defined by hypertensive blood pressure in the office, whereas blood pressure in other situations is normal, for example in ambulatory blood pressure monitoring or home blood pressure measurement.
Angela Maria Geraldo Pierin
doaj  

Corrosion Resistance of Steel/Zinc with Silicate Nanoparticles/Polyurethane Paint Systems in NaCl Solution [PDF]

open access: yes, 2012
Surface characteristics and corrosion behaviour of bare electrogalvanized steel coated with polymer/nano-silicate particles added to the electrogalvanizing bath were studied by scanning electron microscopy (SEM), energy dispersive spectrometer (EDXS) and
Di Sarli, Alejandro Ramón   +2 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

When the White Coat Becomes the White Cassock

open access: green, 2023
Sotirios Apostolakis, Apollonia Lazou
openalex   +1 more source

Differential Expression of Hypertension-Associated MicroRNAs in the Plasma of Patients With White Coat Hypertension

open access: yesMedicine, 2015
White coat hypertension (WCH) is a high cardiovascular risk condition, and a fundamental understanding of the cause and pathophysiology of the disorder is still lacking.
M. Cengiz   +8 more
semanticscholar   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

Total phenol content in seed coat of three cultivars of Phaseolus vulgaris L.

open access: yesBiotecnología Vegetal, 2016
The colors of the common bean (Phaseolus vulgaris L.) are related to some of their properties. The objective of this work was to determine the total phenol content in the seed coat of three different bean cultivars. Seeds of the cultivars 'Delicias 364' (
Yenisey Gutierrez Sánchez   +7 more
doaj  

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

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