Results 321 to 330 of about 4,222,028 (359)
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Do white cells matter in white matter damage?
Trends in Neurosciences, 2001Support is provided for the hypothesis that activated leukocytes, especially monocytes/macrophages, contribute to cerebral white matter damage in extremely low gestational age newborns. Much of the evidence is indirect and comes from analogies to brain diseases in adults, and from models of brain damage in adult and newborn animals.
Scott K. Durum +2 more
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Brain Research Reviews, 1999
Brain and spinal cord white matter are vulnerable to the effects of ischaemia. Reduction of the energy supply leads to a cascade of events including depolarization, influx of Na(+) and the subsequent reverse operation of the membrane protein the Na(+)/Ca(2+) exchanger which ultimately terminates in intracellular Ca(2+) overload and irreversible axonal ...
Petty Margaret, Joseph G Wettstein
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Brain and spinal cord white matter are vulnerable to the effects of ischaemia. Reduction of the energy supply leads to a cascade of events including depolarization, influx of Na(+) and the subsequent reverse operation of the membrane protein the Na(+)/Ca(2+) exchanger which ultimately terminates in intracellular Ca(2+) overload and irreversible axonal ...
Petty Margaret, Joseph G Wettstein
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White matter lactate – Does it matter?
Neuroscience, 2014About half of the human brain is white matter, characterized by axons covered in myelin, which facilitates the high speed of nerve signals from one brain area to another. At the time of myelination, the oligodendrocytes that synthesize myelin require a large amount of energy for this task.
Rinholm, J E, Bergersen, Linda Hildegard
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Impact of white matter hyperintensities on surrounding white matter tracts
Neuroradiology, 2018It is unclear how white matter hyperintensities disrupt surrounding white matter tracts. The aim of this tractography study was to determine the spatial relationship between diffusion characteristics along white matter tracts and the distance from white matter hyperintensities.Diffusion tensor 3-T MRI scans were acquired in 29 participants with white ...
Adrian Crawley +7 more
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A mysterious white matter lesion [PDF]
Acta Neurologica Belgica, 2019 White matter diseases come with a huge number of differential diagnosis. Diagnostic work up in patients with white matter disease is primarily based on neuroradiological findings. Sometimes those findings could mislead a clinician to the wrong diagnosis and hence to unnecessarily diagnostic procedures.
Ivana Markovic, Silvio Basic
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Science, 2003
Scientists have long known that connections somehow go awry in the brains of people with schizophrenia. Now advances in imaging and gene technology are allowing them to trace the axons that connect from neuron to neuron and make up the brain9s white matter.
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Scientists have long known that connections somehow go awry in the brains of people with schizophrenia. Now advances in imaging and gene technology are allowing them to trace the axons that connect from neuron to neuron and make up the brain9s white matter.
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Neurogenetics: white matter matters
Trends in Neurosciences, 2002A group of inherited syndromes characterized by progressive muscle atrophy and sensory dysfunction, collectively referred to as Charcot–Marie–Tooth disease (CMT), has proven to be a hotbed for the identification of novel genetic mutations. CMT syndromes are unusually common (affecting one in every 2200 people), can be dominant, recessive or X-linked ...
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2014
The applications of diffusion tensor imaging (DTI) have increased considerably among both normal and diverse neuropsychiatric populations in recent years. In this chapter, the authors examine the contributions of DTI in identifying profiles of trait-specific connectivity in several groups defined in terms of gender, age, handedness, and general ...
Foteini Christidi +3 more
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The applications of diffusion tensor imaging (DTI) have increased considerably among both normal and diverse neuropsychiatric populations in recent years. In this chapter, the authors examine the contributions of DTI in identifying profiles of trait-specific connectivity in several groups defined in terms of gender, age, handedness, and general ...
Foteini Christidi +3 more
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Imaging of White Matter Lesions
Cerebrovascular Diseases, 2002Magnetic resonance imaging (MRI) is very sensitive for the detection of white matter lesions (WML), which occur even in normal ageing. Intrinsic WML should be separated from physiological changes in the ageing brain, such as periventricular caps and bands, and from dilated Virchow-Robin spaces.
Barkhof, Frederik, Scheltens, Philip
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"Vanishing white matter" (VWM) is a leukodystrophy caused by autosomal recessive pathogenic variants in the genes encoding the subunits of eukaryotic initiation factor 2B (eIF2B). Disease onset and disease course are extremely variable. Onset varies from the antenatal period until senescence. The age of onset is predictive of disease severity.
van der Knaap, Marjo S. +2 more
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van der Knaap, Marjo S. +2 more
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