Results 81 to 90 of about 37,653 (251)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Rapid PCR-based assay for Sclerotinia sclerotiorum detection on soybean seeds

Scientia Agricola, 2015
Caused by Sclerotinia sclerotiorum, white mold is an important seed-transmitted disease of soybean (Glycine max). Incubation-based methods available for the detection and quantification of seed-borne inoculum such as the blotter test, paper roll and Neon-
Edilaine Mauricia Gelinski Grabicoski, David de Souza Jaccoud Filho, Marcos Pileggi, Luciane Henneberg, Marcelo Luiz Cunha Pierre, Cláudio Mauricio Vrisman, Audrei Nisio Gebieluca Dabul   +6 more
doaj   +1 more source

Control of white mold (Sclerotinia sclerotiorum) through plant-mediated RNA interference. [PDF]

Sci Rep, 2023
Walker PL, Ziegler DJ, Giesbrecht S, McLoughlin A, Wan J, Khan D, Hoi V, Whyard S, Belmonte MF.   +8 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Linked candidate genes of different functions for white mold resistance in common bean (Phaseolus vulgaris L) are identified by multiple QTL mapping approaches. [PDF]

Front Plant Sci, 2023
Oladzad A, Roy J, Mamidi S, Miklas PN, Lee R, Clevenger J, Myers Z, Korani W, McClean PE.   +8 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

White mold and Sclerotinia sclerotiorum detection: An ensemble deep learning approach

Smart Agricultural Technology
The white mold disease, caused by the soilborne pathogen Sclerotinia sclerotiorum, is an epidemic and widespread disease affecting common beans and over 400 host plants.
Rubens de Castro Pereira, Díbio Leandro Borges, Justino José Dias Neto, Murillo Lobo, Jr., Ricardo da Silva Torres, Helio Pedrini   +5 more
doaj   +1 more source

Characterization of Transcriptional Responses to Genomovirus Infection of the White Mold Fungus, Sclerotinia sclerotiorum. [PDF]

Viruses, 2022
Pedersen CJ, Marzano SL.
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Polyphasic Characterization of Four Aspergillus Species as Potential Biocontrol Agents for White Mold Disease of Bean. [PDF]

J Fungi (Basel), 2022
Atallah OO, Mazrou YSA, Atia MM, Nehela Y, Abdelrhim AS, Nader MM.   +5 more
europepmc   +1 more source