Results 41 to 50 of about 421,632 (268)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
White pages of biography of Marshal of the Soviet Union L. A. Govorov [PDF]
In the article, for the first time, previously unknown archival documents on the participation of the future Marshal of the Soviet Union L. A. Govorov in White movement in the East of Russia are being introduced into scientific circulation.
A. V. Ganin
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
CRIMEAN KARAITES IN THE ARMED FORCES OF THE SOUTH OF RUSSIA (1918 – 1920)
The paper analyses the information about soldiers and officers of the Voluntary Army of the South of Russia from Crimean Karaites communities who took part in the Civil War.
D. A. Prokhorov
doaj
Movements of White-Headed and White-Backed Vultures
Vultures are the only obligate vertebrate scavengers, and as such provide crucial services as keystone species and support the health and function of ecosystems in which they live. African vultures are a diverse group, with nine species found throughout Sub-Saharan Africa, many with overlapping distributions ...
openaire +2 more sources
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The article is devoted to the issues of the regional markets in the ‘White’ South of Russia during the final period of the Civil War (spring-autumn 1920) which is associated with the activities of the commanding general of the anti-Bolshevik White Army ...
Vasily Tsvetkov , Elena Tsvetkova
doaj +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
The terms “self-determination,” “democracy,” and “national autonomy” were omnipresent after the end of World War I. Yet it was not only actors with revolutionary or nation-state agendas who used these popular slogans.
Thomas Rettig
doaj +1 more source
The London Inter-Allied Conference on the "Russian question" (December 11-13, 1919) is rarely mentioned by historians, but a landmark event in the history of British participation in foreign intervention in Russia - and in a broad sense an interesting ...
Sergei A. Mironyuk
doaj +1 more source

