Results 71 to 80 of about 2,262,533 (310)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Facultative Altitudinal Movements by Mountain White-Crowned Sparrows (Zonotrichia Leucophrys Oriantha) in the Sierra Nevada [PDF]

open access: yes, 2004
Mountain White-crowned Sparrows (Zonotrichia leucophrys oriantha) winter in Mexico and often arrive in the vicinity of their breeding grounds in the Sierra Nevada well before nesting is possible.
Breuner, Creagh W.   +3 more
core   +3 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Conceptualising success and failure for social movements [PDF]

open access: yes, 2009
The paper discusses some of the most significant conceptions of success and failure present in the social movement literature, and highlights the gaps present in these theories.
Saeed, Raza
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

White Ethnic: A Social Concept [PDF]

open access: yes, 2000
Why such a term as white ethnic or ethnic developed and what purposes it served guides this inquiry. Its origins in the wake of the Civil Rights Movement in a context of American immigration history are explored together with its adoption as a ...
Conforti, Joseph M.
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Finding the far right online: an exploratory study of white supremacist websites [PDF]

open access: yes, 2009
White supremacists and the Far Right political movement in the UK have, had considerable success in spreading their messages through Web sites. Some of these Web sites clearly contribute to an enabling environment for racially motivated violence in our ...
Sutton, M, Wright, C
core  

The Alt-Right and Global Information Warfare [PDF]

open access: yes, 2019
The Alt-Right is a neo-fascist white supremacist movement that is involved in violent extremism and shows signs of engagement in extensive disinformation campaigns.
Bevensee, Emmi, Ross, Alexander Reid
core   +3 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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