Results 121 to 130 of about 718,264 (305)

Optical Chaos Generation and Applications

open access: yesAdvanced Photonics Research, EarlyView.
This review comprehensively examines optical chaos generation via feedback, injection, and optoelectronic methods, emphasizing bandwidth enhancement and time‐delay suppression. Applications include chaos‐synchronized secure communication, physical random number generation, chaotic lidar for cm‐level detection, distributed fiber sensing, and terahertz ...
Wenhui Chen   +8 more
wiley   +1 more source

Fiber‐Specific White Matter Alterations in Parkinson's Disease Patients with GBA Gene Mutations [PDF]

open access: hybrid, 2023
Christina Andica   +9 more
openalex   +1 more source

Development of Photo‐Biocatalytic Redox System for Asymmetric Synthesis of Optically Active Amines Using Blue Light and Transaminases. A Case Study Toward Mavacamten

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
Abstract α‐Chiral amines are versatile building blocks for the asymmetric synthesis of optically pure high‐added‐value chemicals, including pharmaceuticals, agrochemicals, and natural products. Herein, we report a one‐pot, two‐step sequential deracemization of racemic sec‐alcohols to optically enriched primary amines throught a photo‐biocatalytic ...
Natalia Antos   +5 more
wiley   +1 more source

The CRL7FBXW8 Complex Controls the Mammary Stem Cell Compartment through Regulation of NUMB Levels

open access: yesAdvanced Science, EarlyView.
In breast cancer (BC), NUMB loss of function (LOF) is common and mainly driven by protein hyper‐degradation. The CRL7FBXW8 complex is the E3 ligase responsible for NUMB degradation. Inhibition of CRL7FBXW8 in NUMB‐LOF BC cells restores NUMB levels, and decreases the number of cancer stem cells and tumorigenic ability in vivo. Targeting CRL7FBXW8 offers
Simone Sabbioni   +16 more
wiley   +1 more source

Nonsuppressible viremia during HIV-1 therapy meets molecular virology [PDF]

open access: yesarXiv
HIV-1 replication can be suppressed with antiretroviral therapy (ART), but individuals who stop taking ART soon become viremic again. Some people experience extended times of detectable viremia despite optimal adherence to ART. In the issue of the JCI, White, Wu, and coauthors elucidate a source of nonsuppressible viremia (NSV) in treatment-adherent ...
arxiv  

Stereotyped Subclones Revealed by High‐Density Single‐Cell Lineage Tracing Support Robust Development

open access: yesAdvanced Science, EarlyView.
Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang   +14 more
wiley   +1 more source

MMT: Mutation Testing of Java Bytecode with Model Transformation -- An Illustrative Demonstration [PDF]

open access: yesarXiv
Mutation testing is an approach to check the robustness of test suites. The program code is slightly changed by mutations to inject errors. A test suite is robust enough if it finds such errors. Tools for mutation testing usually integrate sets of mutation operators such as, for example, swapping arithmetic operators; modern tools typically work with ...
arxiv  

Prevalence and Predictors of BRCA1 and BRCA2 Mutations in a Population-Based Study of Breast Cancer in White and Black American Women Ages 35 to 64 Years [PDF]

open access: bronze, 2006
Kathleen E. Malone   +21 more
openalex   +1 more source

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