De Novo Design of Integrin α5β1 Modulating Proteins to Enhance Biomaterial Properties
NeoNectins are de novo‐designed miniproteins that selectively bind and stabilize the extended open form of integrin α5β1. When grafted onto biomaterials including hydrogel and titanium, they promote cell attachment and spreading in vitro and promoting tissue integration and bone growth in animal models, demonstrating broad potential for regenerative ...
Xinru Wang+25 more
wiley +1 more source
ACTA2 leukovasculopathy: A rare pediatric white matter disorder
A 3-year-old girl presented with ataxia, dilated pupils, and behavioral change prompting work up for stroke. Her medical history included chronic mydriasis and patent ductus arteriosus requiring aortoplasty.
Tonia M. Sabo, MD+4 more
doaj
Ectopic White Matter Neurons, a Developmental Abnormality That May Be Caused by thePSEN1S169L Mutation in a Case of Familial AD with Myoclonus and Seizures [PDF]
Masaki Takao+11 more
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An eleven-year history of Vanishing White Matter Disease in an adult patient with no cognitive decline and EIF2B5 mutations. A case report [PDF]
Lucia Trevisan+9 more
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Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi+4 more
wiley +1 more source
Different mutation of the XLRS1 gene causes juvenile retinoschisis with retinal white flecks [PDF]
Yoshihiro Hotta
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Engineering Bacterial Secretion Systems for Enhanced Tumor Imaging and Surgical Guidance
This study presents a novel contrast agent platform, Streptavidin Associated Salmonella (SAS), for fluorescence image guided surgery. SAS selectively colonizes tumors and secretes streptavidin, enabling precise delineation of invasive tumor margins with prolonged signal retention.
Dohee Lee+14 more
wiley +1 more source
The Arabidopsis immutans Mutation Affects Plastid Differentiation and the Morphogenesis of White and Green Sectors in Variegated Plants [PDF]
Maneesha Aluru+3 more
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EIF2B2 gene mutation causing early onset vanishing white matter disease: a case report [PDF]
Ilaria Filareto+7 more
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We report a 3.2 Å cryoEM structure of functional amyloid protein FapC from Pseudomonas sp. UK4, an essential component of bacterial biofilm, which reveals a Greek key‐shaped protofilament, supports bioinformatically determined motifs, nuances AlphaFold predictions, emphasizes heterogeneous cross‐β stacking in amyloid cross‐seeding and shows strain ...
Yanting Jiang+13 more
wiley +1 more source