Results 141 to 150 of about 3,299,410 (331)

Spotting the Pattern: A Review on White Coat Color in the Domestic Horse

Animals
Traits such as shape, size, and color often influence the economic and sentimental value of a horse. Around the world, horses are bred and prized for the colors and markings that make their unique coat patterns stand out from the crowd.
Aiden McFadden, Micaela Vierra, Katie Martin, Samantha A. Brooks, Robin E. Everts, Christa Lafayette   +5 more
doaj   +1 more source

Familial tumoral calcinosis and testicular microlithiasis associated with a new mutation of GALNT3 in a white family [PDF]

, 2006
Maria Francesca Campagnoli, Angela Pucci, Emanuela Garelli, Adriana Carando, Claudio Defilippi, R. Lala, G. Ingrosso, Irma Dianzani, Marco Forni, Ugo Ramenghi   +9 more
openalex   +1 more source

Wolff–Parkinson–White syndrome: De novo variants and evidence for mutational burden in genes associated with atrial fibrillation [PDF]

, 2020
Zeynep Coban‐Akdemir, Wu‐Lin Charng, Mahshid S. Azamian, Ingrid S. Paine, Jaya Punetha, Christopher M. Grochowski, Tomasz Gambin, Santiago O. Valdés, Bryan C. Cannon, Gladys Zapata, Patricia Hernandez, Shalini N. Jhangiani, HarshaVardhan Doddapaneni, Jianhong Hu, Fatima Boricha, Donna M. Muzny, Eric Boerwinkle, Yaping Yang, Richard A. Gibbs, Jennifer E. Posey, Xander H.T. Wehrens, John W. Belmont, Jeffrey J. Kim, Christina Y. Miyake, James R. Lupski, Seema R. Lalani   +25 more
openalex   +1 more source

Stereotyped Subclones Revealed by High‐Density Single‐Cell Lineage Tracing Support Robust Development

Advanced Science, EarlyView.
Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang, Zizhang Li, Jingyu Chen, Wenjing Yang, Xingxing He, Peng Wu, Feng Chen, Ziwei Zhou, Chenze Ren, Yuyan Shan, Xiewen Wen, Vassily A. Lyubetsky, Leonid Yu. Rusin, Xiaoshu Chen, Jian‐Rong Yang   +14 more
wiley   +1 more source

Viral‐Mediated Connexin 26 Expression Combined with Dexamethasone Rescues Hearing in a Conditional Gjb2 Null Mice Model

Advanced Science, EarlyView.
AAV2.7m8 serotype combined with the gfaABC1D promoter targets infection of supporting cells (SCs). AAV2.7m8‐gfaABC1D‐Gjb2 administration to mice results in excessive immune responses. The combination of AAV2.7m8‐gfaABC1D‐Gjb2 with dexamethasone (DEX) shows a synergistic effect and enhances the gene therapy effect in a conditional Cx26 null mice model ...
Xiaohui Wang, Li Zhang, Sen Chen, Le Xie, Yue Qiu, Chenyang Kong, Ge Yin, Weijia Kong, Yu Sun   +8 more
wiley   +1 more source

A Determination of the Magnitude of the Cell “Sensitive Volume” Associated with the White-Eye Mutation in X-Rayed Drosophila—

, 1936
Caryl P. Haskins, E. V. Enzmann
openalex   +1 more source

C3H/HeJ mice carrying a toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat diet [PDF]

, 2007
Marjorie Poggi, Delphine Bastelica, Philippe Gual, Miguel A. Iglesias, Thierry Grémeaux, Claude Knauf, Franck Peiretti, Monique Verdier, I. Juhan‐Vague, Jean‐François Tanti, Rémy Burcelin, Marie‐Christine Alessi   +11 more
openalex   +1 more source

NOX2 Contributes to High‐Frequency Outer Hair Cell Vulnerability in the Cochlea

Advanced Science, EarlyView.
This study first identifies NOX2 as a differentially expressed gene related to oxidative damage in the apical and basal turns through single‐cell RNA sequencing. NOX2 gene knockout mitigates OHCs damage caused by neomycin and noise and enhances Nrf2 expression and nuclear translocation.
Meihao Qi, Zejun Gao, Yang Qiu, Renfeng Wang, Keyong Tian, Bo Yue, Xinyu Zhang, Peng Zhang, Ziqi Wu, Qingwen Zhu, Zhenzhen Liu, Zhuoyao Ma, Xueying Zhou, Yu Han, Jun Chen, Jianhua Qiu, DingJun Zha   +16 more
wiley   +1 more source

AAVR Expression is Essential for AAV Vector Transduction in Sensory Hair Cells

Advanced Science, EarlyView.
Decreased sensitivity to AAV vector transduction in the outer hair cells (OHCs) of adult mice is primarily attributed to reduction of AAVR (Kiaa0319l; Au040320). Knockout of AAVR reduces AAV vector transduction efficiency in both inner hair cells (IHCs) and OHCs in neonatal mice.
Fan Wu, Guisheng Chen, Rui Hu, Peiwen Liu, Jintao Lou, Wenji Zhao, Zuhong He, Suhua Sha, Yiqing Zheng   +8 more
wiley   +1 more source

Structural and thermodynamic analysis of compensating mutations within the core of chicken egg white lysozyme.

, 1992
Keith P. Wilson, Bruce A. Malcolm, Brian W. Matthews   +2 more
openalex   +1 more source