Results 171 to 180 of about 694,722 (327)

High mutation rate in prolactin intron 2 regulates egg-laying performance in Wanjiang white goose [PDF]

, 2011
Jie Chen, Genlin Wang, Yafei Cai
openalex   +1 more source

Stereotyped Subclones Revealed by High‐Density Single‐Cell Lineage Tracing Support Robust Development

Advanced Science, EarlyView.
Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang, Zizhang Li, Jingyu Chen, Wenjing Yang, Xingxing He, Peng Wu, Feng Chen, Ziwei Zhou, Chenze Ren, Yuyan Shan, Xiewen Wen, Vassily A. Lyubetsky, Leonid Yu. Rusin, Xiaoshu Chen, Jian‐Rong Yang   +14 more
wiley   +1 more source

Single-subject classification of presymptomatic frontotemporal dementia mutation carriers using multimodal MRI

NeuroImage: Clinical, 2019
Background: Classification models based on magnetic resonance imaging (MRI) may aid early diagnosis of frontotemporal dementia (FTD) but have only been applied in established FTD cases.
Rogier A. Feis, Mark J.R.J. Bouts, Jessica L. Panman, Lize C. Jiskoot, Elise G.P. Dopper, Tijn M. Schouten, Frank de Vos, Jeroen van der Grond, John C. van Swieten, Serge A.R.B. Rombouts   +9 more
doaj  

Cutaneous white spots in a child with polycystic kidneys: a clue to TSC2/PKD1 gene mutation

, 2000
Markus Sperandio, Lutz W. D. Weber, A. Jauch, Bart Janssen, Otto Mehls, Franz Schaefer   +5 more
openalex   +1 more source

White matter lesions in FTLD: distinct phenotypes characterize GRN and C9ORF72 mutations [PDF]

, 2016
Fatima Ameur, Olivier Colliot, Paola Caroppo, Sébastian Ströer, Didier Dormont, Alexis Brice, Carole Azuar, Bruno Dubois, Isabelle Le Ber, Anne Bertrand   +9 more
openalex   +1 more source

A Shank Color Mutation in Cornell Random Bred S.C. White Leghorns

Poultry Science, 1974
Abstract A genetic variant displaying green shanks, first noted among pullets of the Cornell random bred stock has been shown to be controlled by a sex linked recessive gene “idc” at the “Id” locus affecting the deposition of melanin in the dermis of the shank skin. An allele other than “id” is suggested since most mutants with green shanks and white
openaire   +3 more sources

Viral‐Mediated Connexin 26 Expression Combined with Dexamethasone Rescues Hearing in a Conditional Gjb2 Null Mice Model

Advanced Science, EarlyView.
AAV2.7m8 serotype combined with the gfaABC1D promoter targets infection of supporting cells (SCs). AAV2.7m8‐gfaABC1D‐Gjb2 administration to mice results in excessive immune responses. The combination of AAV2.7m8‐gfaABC1D‐Gjb2 with dexamethasone (DEX) shows a synergistic effect and enhances the gene therapy effect in a conditional Cx26 null mice model ...
Xiaohui Wang, Li Zhang, Sen Chen, Le Xie, Yue Qiu, Chenyang Kong, Ge Yin, Weijia Kong, Yu Sun   +8 more
wiley   +1 more source

Single-subject classification of presymptomatic frontotemporal dementia mutation carriers using multimodal MRI

NeuroImage: Clinical, 2018
Background: Classification models based on magnetic resonance imaging (MRI) may aid early diagnosis of frontotemporal dementia (FTD) but have only been applied in established FTD cases.
Rogier A. Feis, Mark J.R.J. Bouts, Jessica L. Panman, Lize C. Jiskoot, Elise G.P. Dopper, Tijn M. Schouten, Frank de Vos, Jeroen van der Grond, John C. van Swieten, Serge A.R.B. Rombouts   +9 more
doaj  

Comparison of Frequency and Sensitivity of BCR-ABL1 Kinase Domain Mutations in Asian and White Patients With Imatinib-resistant Chronic–Phase Chronic Myeloid Leukemia [PDF]

, 2018
Hawk Kim, SooHyun Kim, Hyeoung‐Joon Kim, Yeo‐Kyeoung Kim, Jae‐Yong Kwak, Ho‐Young Yhim, Sung‐Hyun Kim, Young Rok, Sukjoong Oh, Sung‐Eun Lee, Saengsuree Jootar, Jiu Wei Cui, Dong‐Wook Kim   +12 more
openalex   +1 more source

NOX2 Contributes to High‐Frequency Outer Hair Cell Vulnerability in the Cochlea

Advanced Science, EarlyView.
This study first identifies NOX2 as a differentially expressed gene related to oxidative damage in the apical and basal turns through single‐cell RNA sequencing. NOX2 gene knockout mitigates OHCs damage caused by neomycin and noise and enhances Nrf2 expression and nuclear translocation.
Meihao Qi, Zejun Gao, Yang Qiu, Renfeng Wang, Keyong Tian, Bo Yue, Xinyu Zhang, Peng Zhang, Ziqi Wu, Qingwen Zhu, Zhenzhen Liu, Zhuoyao Ma, Xueying Zhou, Yu Han, Jun Chen, Jianhua Qiu, DingJun Zha   +16 more
wiley   +1 more source