Results 191 to 200 of about 731,846 (342)

Mutation of the RIIβ Subunit of Protein Kinase A Differentially Affects Lipolysis but Not Gene Induction in White Adipose Tissue

, 1999
Josep V. Planas, David E. Cummings, Rejean L. Idzerda, G. Stanley McKnight   +3 more
openalex   +1 more source

Allele frequencies of hemojuvelin gene (HJV) I222N and G320V missense mutations in white and African American subjects from the general Alabama population [PDF]

, 2004
James C. Barton, Charles Rivers, Sandrine Niyongere, Sean B Bohannon, Ronald T. Acton   +4 more
openalex   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Tumor Mutations in Minority Populations Versus Non-Hispanic Whites Across Tumor Types. [PDF]

JCO Precis Oncol
Coy J, Doan I, Chabot-Richards D, Kosich M, Pankratz VS, Kerr L, Jawadi S, Tawfik B.   +7 more
europepmc   +1 more source

Differences in Tumor VHL Mutation and Hypoxia-inducible Factor 2α Expression Between African American and White Patients with Clear Cell Renal Cell Carcinoma

, 2019
Catherine L. Callahan, Lee E. Moore, Petra H. Lenz, W. Marston Linehan, Michael L. Nickerson, Nathaniel Rothman, Mark P. Purdue   +6 more
openalex   +2 more sources

Functional analysis of recently identified mutations in eukaryotic translation initiation factor 2Bɛ (eIF2Bɛ) identified in Chinese patients with vanishing white matter disease [PDF]

, 2011
Xuerong Leng, Ye Wu, Xuemin Wang, Yanxia Pan, Jingmin Wang, Jiao Li, Li Du, Lifang Dai, Xiru Wu, Christopher G. Proud, Yuwu Jiang   +10 more
openalex   +1 more source

Macrophages Mediate Mesoscale Brain Mechanical Homeostasis

Advanced Materials, EarlyView.
We investigated the role of infiltrating immune cells in sculpting the developing brain. Using Brillouin microscopy and active microrheology, we found microglia actively maintain tissue viscoelasticity. Moreover, colony stimulating factor one receptor (CSF1R)‐driven stromal remodeling alters brain mechanics in vivo. These findings link immune activity,
Woong Young So, Bailey Johnson, Patricia B. Gordon, Kevin S. Bishop, Hyeyeon Gong, Hannah A Burr, Jack Rory Staunton, Chenchen Handler, Khanh Loan Ly, Raman Sood, Giuliano Scarcelli, Kandice Tanner   +11 more
wiley   +1 more source

Large DNA and protein language models enhance discovery of deleterious mutations in maize. [PDF]

Genome Biol
Wang Y, He C, Wang Q, Li R, Qin Y, Wang H, Gou M, Zhang X, Li H, Huang Q, Liu X, Yang J, White FF, Fu J, Liu S, Zheng J.   +15 more
europepmc   +1 more source

Mutation at the anophthalmic white locus in Syrian hamsters: haploinsufficiency in the Mitf gene mimics human Waardenburg syndrome type 2 [PDF]

, 1998
Colin A. Hodgkinson, Atsuo Nakayama, Hua Li, Lori Beth Swenson, Karin Opdecamp, James H. Asher, Heinz Arnheiter, Thomas Gläser   +7 more
openalex   +1 more source

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source