Prognosis and treatment response stratification according to loss of proofreading (LOP) <i>POLE</i> variants. [PDF]
J Immunother CancerMaddalena G +11 more
europepmc +1 more source
The Vegan Villain Sets Out to The End of Summer: Functionalized Coatings as Biohybrid UV‐Sensors
Advanced Materials Interfaces, EarlyView.This study introduces biohybrid coatings incorporating E. coli biomass expressing photoconvertible fluorescent proteins as UV‐A responsive elements. Upon irradiation at 400 nm, the coatings exhibit an irreversible fluorescence shift from green to red within 15 min. Notably, the photoconversion capability is retained after >1 year of storage.
Amelie Skopp +3 more
wiley +1 more source
Plasma-based next generation sequencing in advanced non-small cell lung cancer (NSCLC): significance in diagnosis and treatment in Asian patients. [PDF]
BMC CancerWu CH, Wu X, Hu X, Kennedy A, Pai L.
europepmc +1 more source
Sp alpha I/78: a mutation of the alpha I spectrin domain in a white kindred with HE and HPP phenotypes [PDF]
, 1989 MC Lecomte +9 more
openalex +1 more source
Phenotypic effects of a fertility mutation in Norwgain White Sheep
, 2013 Norwegian White Sheep (NWS) is a synthetic breed that results from crosses between local Norwegian and foreign breeds. This breed is mainly kept for the meat production, and litter size is therefore a trait of large economic value. A mutation in the ovine GDF9 gene (c.1111G>A) on chromosome 5 was recently found to be associated with increased litter ...
openaire +1 more source
Biogenic Next‐Gen CPL Emitters: Strategies with Proteins, Polysaccharides, and Nucleotides
Advanced Optical Materials, EarlyView.Biogenic molecules such as proteins, peptides, saccharides, and DNA can act as natural scaffolds for generating circularly polarized luminescence (CPL). This review highlights recent strategies exploiting these inherently chiral frameworks to achieve light emission with controllable handedness under unpolarized excitation, bridging biological ...
Ricardo Chavez‐Jimenez +4 more
wiley +1 more source
Advanced Therapeutics, EarlyView.This study characterizes a camelid antibody (B10) with potent neutralizing activity against SARS‐CoV‐2 Wildtype and Omicron variants. Through binding assays, epitope mapping, pseudovirus neutralization, and AI‐driven modeling, the antibody is shown to target conserved RBD regions in a closed Spike conformation.
Katja Hanack +13 more
wiley +1 more source
Human herpesvirus 6B infection in an adult with hemophagocytic lymphohistiocytosis carrying an UNC13D mutation: a case report and literature review. [PDF]
Front ImmunolXiao P +5 more
europepmc +1 more source
Advanced Therapeutics, EarlyView.A bi‐functional liposomal system is developed to enhance melanoma therapy, combining mApoE‐mediated targeting of LDLR‐expressing tumor cells with MMP2‐responsive drug release. Loaded with Pimasertib, the liposomes improve intracellular delivery, reduce melanoma viability, and inhibit 3D spheroid growth and invasiveness.
Antonio Renda +14 more
wiley +1 more source