Results 211 to 220 of about 717,864 (344)

Comparative Dermoscopic Analysis of Melanoma In Situ Versus Thin Invasive Melanoma Considering BRAF Mutational Status. [PDF]

J Clin Med
Zboraș I, Ungureanu L, Șenilă SC, Gaál OI, Gligor-Popa ȘA, Crișan D, Șușman S, Vesa ȘC, Cosgarea R.   +8 more
europepmc   +1 more source

Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism

Advanced Science, EarlyView.
Melanoma, an aggressive skin cancer, arises from dynamic interactions between genetic, environmental, and lifestyle factors. This review explores how age, gender, obesity, diet, exercise, smoking, alcohol, UV exposure, circadian rhythms, and medications influence melanoma risk and progression.
Hanbin Wang, Hengxiang Zhang, Yuqi Zhou, Chunying Li, Weinan Guo   +4 more
wiley   +1 more source

Case report: A special case of pneumonia with a novel STAT3 mutation and Talaromyces marneffei infection. [PDF]

Respir Med Case Rep
Zhang F, Zhu X, Yang J.
europepmc   +1 more source

Developmental Hypoxia Enhances Kidney Organoid Complexity and Maturity

Advanced Science, EarlyView.
The current bottleneck in metanephric mesenchyme (MM)‐derived nephron organoid development is the absence of a connected network of collecting ducts (CD) derived from the ureteric bud (UB). To address this limitation, this study proposes a hypoxia‐based differentiation method that mimics the natural renal developmental environment, enabling the ...
Hyeonji Lim, Dohui Kim, Haejin Yoon, Joo H. Kang, Yong Jun Kim, Dong Sung Kim, Tae‐Eun Park   +6 more
wiley   +1 more source

CADASIL or <i>NOTCH3</i> mutaion spectrum diseases? Interpretation of <i>NOTCH3</i> mutations and clinical heterogeneity in CADASIL. [PDF]

Front Neurol
Wang Y, Liu Y, Mo H, Han Y, Jing Y, Deng F.   +5 more
europepmc   +1 more source

BACK MUTATION IN DROSOPHILA MELANOGASTER. II. DATA ON ADDITIONAL YELLOW AND WHITE MUTANTS [PDF]

, 1962
M. M. Green
openalex   +1 more source

Calhm6 Governs Macrophage Polarization Through Chp1‐Camk4‐Creb1 Axis and Ectosomal Delivery in Inflammatory Responses

Advanced Science, EarlyView.
Calhm6 drives M2 macrophage polarization via the Chp1‐Camk4‐Creb1 axis, suppressing inflammation through calcium‐dependent ectosomal delivery. Calhm6 deficiency enhances M1 responses, boosting bactericidal activity but exacerbating tissue damage. LPS/IFNγ upregulate Calhm6 via Irf1, while IL‐4/Stat6 inhibits it, balancing immune outcomes.
Yanlong Xin, Xiaofan Xiong, Yan Zhang, Siyu Zhang, Shuting Zhang, Yu Yang, Yingxue Liang, Lulu Zang, Xi Chen, Wenjuan Li, Issam Halalmeh, Rui Zhou, Zongfang Li, Haowen Liu, Jing Geng   +14 more
wiley   +1 more source

Alterations in MRI-visible perivascular spaces precede dementia diagnosis by 18 years in autosomal dominant Alzheimer's disease. [PDF]

Alzheimers Dement
Leone R, Kobeleva X, Rowe B, Choupan J, Ringman JM, Barisano G.   +5 more
europepmc   +1 more source

Sanggenol L Enhances Temozolomide Drug Sensitivity by Inhibiting Mitophagy and Inducing Apoptosis Through the Regulation of the TRIM16‐OPTN Axis in Glioblastoma

Advanced Science, EarlyView.
Sanggenol L, a flavonoid from mulberry, enhances glioblastoma sensitivity to temozolomide by inhibiting mitophagy and inducing apoptosis through TRIM16‐mediated OPTN degradation. In animal studies, liposomal delivery of Sanggenol L significantly improves the efficacy of its combination with TMZ, providing new insights into glioblastoma treatment ...
Hongbo Chang, Jianbing Hou, Xin Hu, Nana Hou, Minghao Xu, Yi Du, Jingyang Xu, Yongzhao Wang, Zhuohao Xie, Junbo Shi, Yundong Zhang, Hongjuan Cui   +11 more
wiley   +1 more source

Metabolic syndrome and ADRB3 gene polymorphism in severely obese patients from South Italy [PDF]

, 2007
C Finelli, C Nardelli, F Contaldo, F Pasanisi, G Labruna, G Oriani, G Salvatori, L Sacchetti, P Buono, R Bracale   +9 more
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