Results 231 to 240 of about 694,722 (327)

Targeted seed EMS mutagenesis reveals a basic helix-loop-helix transcription factor underlying male sterility in sorghum. [PDF]

Genetics
Xiao Y, Khangura RS, Wang Z, Dilkes BP, Eveland AL.   +4 more
europepmc   +1 more source

Gastrula‐Premarked Posterior Enhancer Primes Posterior Tissue Development Through Cross‐Talk with TGF‐β Signaling Pathway

Advanced Science, EarlyView.
A gastrula‐premarked enhancer within the first intron of Cdx2 governs posterior embryonic development via both regulating Cdx2 expression in cis and coordinating TGF‐β signaling in trans to ensure proper posterior body development. Functional rescue in gastruloids reveals a Cdx2‐independent pathway, highlighting p‐Enh‐eRNA as key epigenetic ...
Yingying Chen, Fengxiang Tan, Qing Fang, Lin Zhang, Jiaoyang Liao, Penglei Shen, Yun Qian, Mingzhu Wen, Rui Song, Yonggao Fu, He Jax Xu, Ran Wang, Cheng Li, Zhen Shao, Jinsong Li, Naihe Jing, Xianfa Yang   +16 more
wiley   +1 more source

Outcomes of genetic testing for Usher syndrome in a diverse population cohort from South Florida. [PDF]

Hum Genomics
Cromar ZJ, Chen R, Riesgo TJ, Yan D, Verma LD, Chen Z, Blanton SH, Lam BL, Liu XZ.   +8 more
europepmc   +1 more source

Advanced Microfluidics for Single Cell‐Based Cancer Research

Advanced Science, EarlyView.
Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro, Marta Aranda Palomer, Margarida Esteves, Carolina Rodrigues, José Maria Fernandes, Francisca Oliveira, Alexandra Teixeira, Carlos Honrado, Lorena Dieguez, Sara Abalde‐Cela, Miguel Xavier   +10 more
wiley   +1 more source

Management of multiple primary prostate malignant tumors: case report of synchronous prostatic adenocarcinoma and lymphoma. [PDF]

Front Oncol
Zhuang W, Wu H, Cai Z, Cai N, Liu W, Liu W.   +5 more
europepmc   +1 more source

Analysis of a catalytic pathway via a covalent adduct of D52E hen egg white mutant lysozyme by further mutation [PDF]

, 1999
Yuji Ito, Ryota Kuroki, Yoko Ogata, Yoshio Hashimoto, Kazuhisa Sugimura, Taiji Imoto   +5 more
openalex   +1 more source

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

Advanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang, Feng Gao, Liqun Yu, Haokun Chen, Rongrong Zhu   +4 more
wiley   +1 more source

Amyloid-β plaque-associated microglia drive TSPO upregulation in Alzheimer's disease. [PDF]

Acta Neuropathol
Martinez-Perez DA, McGlothan JL, Rodichkin AN, Abilmouna K, Bursac Z, Lopera F, Villegas-Lanau CA, Guilarte TR.   +7 more
europepmc   +1 more source

Uric Acid in Anopheles Mosquitoes (Diptera: Culicidae): Effects of Collarless, Stripe, and White Mutations [PDF]

, 1996
Mark Q. Benedict, Allen Carson Cohen, Anton J. Cornel, Donald L. Brummett   +3 more
openalex   +1 more source

A MXene‐Based Nanothermal Knife Inhibits Aggresome‐Mediated Persister Formation for Preventing Dental Caries

Advanced Science, EarlyView.
Early childhood caries (ECC) involves cariogenic persisters that evade antimicrobial treatment. Persisters achieve this by downregulating heat shock proteins (HSPs) and formation of protein aggregates. Ti3C2 MXene‐based photothermal therapy (PTT) acts as a “nanothermal knife,” disrupting membranes, upregulating HSPs, inhibits aggregates, prevents ...
Yinyin Zhang, Leilei Yang, Jing jiao, Wenshuai Li, Sen Lin, Xianlong Zong, Haoyang Qin, Danfeng Liu, Rui Li   +8 more
wiley   +1 more source