Results 261 to 270 of about 694,722 (327)

Bacteria Optimize Tumble Bias to Strategically Navigate Surface Constraints

Advanced Science, EarlyView.
The study investigates how Escherichia coli optimizes tumble bias (TB) to navigate surface constraints effectively. Using single‐cell tracking and modeling, it reveals that bacterial surface residence time decreases with increasing TB, stabilizing near the wild‐type mean TB (≈0.25), where surface diffusivity peaks.
Antai Tao, Guangzhe Liu, Rongjing Zhang, Junhua Yuan   +3 more
wiley   +1 more source

Inherited prion disease caused by a novel frameshift mutation of <i>PRNP</i> resulting in protein truncation at codon 157. [PDF]

J Alzheimers Dis
Holm-Mercer L, Mok TH, Sequeira D, Coysh T, Rudge P, Ramadan H, Darwent L, Campbell T, Murphy T, Smith C, Ritchie D, Brandner S, Jaunmuktane Z, Collinge J, Mead S.   +14 more
europepmc   +1 more source

Attenuated Nuclear Tension Regulates Progerin‐Induced Mechanosensitive Nuclear Wrinkling and Chromatin Remodeling

Advanced Science, EarlyView.
The premature aging‐related progerin leads to defective nuclear morphology and is associated with disrupted molecular coupling between the extranuclear cytoskeleton and lamin‐associated nuclear envelope. It is discovered that progerin expression reduces nuclear tension, forms nuclear wrinkling, and enhances chromatin dynamics, thereby regulating ...
Ji‐Eun Park, Juhyeon Jo, Kun Xu, Sun‐Ah Lee, Seong‐Beom Han, YigJi Lee, Won‐Ki Cho, Bo Li, Soo Hyun Kim, Dong‐Hwee Kim   +9 more
wiley   +1 more source

Coronoidectomy for Alleviating Restricted Mouth Opening in Masticatory Muscle Tendon-Aponeurosis Hyperplasia: Integration With Genetic Mutation Analysis. [PDF]

Case Rep Dent
Zhang H, Wang W, Wen L.
europepmc   +1 more source

THE GENETICS OF ARTEMIA SALINA. II. WHITE EYE, A SEX-LINKED MUTATION

, 1963
Sarane T. Bowen
openalex   +2 more sources

The Multitarget Compound ZLY032 Achieves Treatment of Chronic Wounds

Advanced Science, EarlyView.
ZLY032, a dual free fatty acid receptor 1/peroxisome proliferator‐activated receptor δ agonist, accelerates wound healing in normal/diabetic/methicillin‐resistant Staphylococcus aureus‐infected models by promoting angiogenesis, reducing inflammation, and exhibiting antibacterial activity via argininosuccinate lyase targeting, with demonstrated efficacy
Manyu Gong, Zhiyuan Du, Tiantian Gong, Yu Wang, Chenchen Yin, Bosi Sun, Zijia Liu, Lianru Chen, Zibin Liao, Wenxin Wang, Tianjiao Zhao, Yifei Wang, Ying Dong, Kexin Wang, Mengru Ma, Weijun Li, Jiacheng Li, Haodong Li, Congcong Lin, Ying Zhang, Yu Liu, Xin Liu, Tao Ban, Hongxia Bao, Ying Zhang, Yang Zhang, Zheng Li, Lei Jiao   +27 more
wiley   +1 more source

Pitfalls in the diagnosis of apparent homozygous mutations: two cases of IL10RA deficiency inflammatory bowel disease and a literature review. [PDF]

Orphanet J Rare Dis
Shi X, Ye Z, Qian L, Hu W, Yang Y, He C, Huang Z, Wu B, Huang Y.   +8 more
europepmc   +1 more source

Structural Variations Associated with Adaptation and Coat Color in Qinghai‐Tibetan Plateau Cattle

Advanced Science, EarlyView.
This study reveals the landscape of structural variants in Qinghai‐Tibetan Plateau cattle through long‐read sequencing. Discoveries include metabolic and oxygen‐regulation gene variants, along with a 2‐Mb KIT‐containing inversion and translocations responsible for cattle gray coat. These findings highlight the significant role of structural variants in
Xiaoting Xia, Fuwen Wang, Xiaoyu Luo, Shuang Li, Yang Lyu, Yining Zheng, Zhijie Ma, Kaixing Qu, Rende Song, Jianyong Liu, Jicai Zhang, Basang Wangdui, Basang Zhuzha, Suolang Quji, Li Zhao, Silang Wangmu, Ciren Luobu, Nima Cangjue, Danzeng Luosang, Suolang Sizhu, Haijian Cheng, Ruizhe Li, Zhipeng Wu, Ruihua Dang, Yongzhen Huang, Xianyong Lan, Luohao Xu, Haifei Hu, WaiYee Low, Zhuqing Zheng, Yu Wang, Yuanpeng Gao, Lu Deng, Johannes A. Lenstra, Jianlin Han, Xueyi Yang, Wenfa Lyu, Bizhi Huang, Chuzhao Lei, Ningbo Chen   +39 more
wiley   +1 more source

A case report of massive pulmonary embolism in a pregnant woman with undiagnosed thrombophilia: Management strategies and timing for thrombophilia screening. [PDF]

Radiol Case Rep
Bouyaddid S, Ouaddouh Y, Bazid Z, El Ouafi N, Ismaili N.   +4 more
europepmc   +1 more source

Coupling antitoxins and blue/white screening with parAB /resolvase mutation as a strategy for Salmonella spp. plasmid curing

Dereje D. Gudeta, Shaohua Zhao, Nesreen Aljahdali, Steven L. Foley   +3 more
openalex   +1 more source