Results 21 to 30 of about 718,214 (259)
Mutation Based Testing of P Systems [PDF]
, 2009 Although testing is an essential part of software development, until recently, P system testing has been completely neglected. Mutation testing (mutation analysis) is a structural software testing method which involves modifying the program in small ...
Gheorgue, Marian, Ipate, Florentin
core +3 more sources
, 2020 We describe and investigate a connection between the topology of isolated singularities of plane curves and the mutation equivalence, in the sense of cluster algebra theory, of the quivers associated with their morsifications.Comment: Major revision and ...
Fomin, Sergey +3 more
core +1 more source
Knot Floer homology, genus bounds, and mutation [PDF]
, 2003 In an earlier paper, we introduced a collection of graded Abelian groups $\HFKa(Y,K)$ associated to knots in a three-manifold. The aim of the present paper is to investigate these groups for several specific families of knots, including the Kinoshita ...
Ozsvath, Peter, Szabo, Zolta
core +4 more sources
Peripheral Innate Immune Activation Correlates With Disease Severity in GRN Haploinsufficiency. [PDF]
, 2019 Objective: To investigate associations between peripheral innate immune activation and frontotemporal lobar degeneration (FTLD) in progranulin gene (GRN) haploinsufficiency. Methods: In this cross-sectional study, ELISA was used to measure six markers of
Allen, Isabel Elaine +16 more
core +2 more sources
A clinical review on megalencephaly: A large brain as a possible sign of cerebral impairment. [PDF]
, 2017 Megalencephaly and macrocephaly present with a head circumference measurement 2 standard deviations above the age-related mean. However, even if pathologic events resulting in both megalencephaly and macrocephaly may coexist, a distinction between these ...
Corsello G +6 more
core +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Presence of the ABCB1 (MDR1) deletion mutation causing ivermectin hypersensitivity in certain dog breeds in Belgium [PDF]
, 2009 Hypersensitivity to ivermectin and certain other drugs in Collies and related breeds is caused by a 4-base pair deletion mutation in the ABCB1 gene, better known as the MDR1 gene, encoding P-glycoprotein.
Daminet, Sylvie +9 more
core +2 more sources
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
A common phytoene synthase mutation underlies white petal varieties of the California poppy. [PDF]
, 2019 The California poppy (Eschscholzia californica) is renowned for its brilliant golden-orange flowers, though white petal variants have been described.
Gong, Xue +2 more
core +1 more source
FEBS Letters, EarlyView.Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston +7 more
wiley +1 more source