Results 291 to 300 of about 694,722 (327)

Visualization of the Spiral Ganglion Neuron in Vivo Using a Novel 177Lu Nuclear Molecule Label

Advanced Science, EarlyView.
The study developed and validated a radionuclide‐labeled anti‐VGLUT1 antibody probe for the first nuclear imaging of cochlear spiral ganglion neurons (SGNs) in vivo. This approach may provide aid in screening candidates suitable for CI surgery by quantifying the number of surviving SGNs, and predicting the potential for postoperative hearing ...
Chenyang Kong, Xiaohui Wang, Jintao Yu, Li Wen, Chengwen Zheng, Ge Yin, Kai Xu, Weiwei He, Hao Wang, Xiaoli Lan, Dawei Jiang, Yu Sun   +11 more
wiley   +1 more source

Intestinal Clock Promotes Cognitive Memory Through Adenosine Signaling

Advanced Science, EarlyView.
The intestinal clock controls the expression of an adenosine enzyme that modulates systemic adenosine level and A1R signaling in the hippocampus, and in turn, cognitive function involving long‐term potentiation and BDNF‐dependent synaptic changes.
Min Chen, Fugui Zhang, Yifei Xiao, Xuejun Jiang, Zhiqian Yan, Jinyi Wang, Xiting Lv, Jialu Cui, Linna Ha, Hui Chen, Yongkang Dang, Zifei Qin, Jing Yang, Baojian Wu   +13 more
wiley   +1 more source

ER‐phagy Activation by AMFR Attenuates Cardiac Fibrosis Post‐Myocardial Infarction via mTORC1 Pathway

Advanced Science, EarlyView.
By catalyzing FAM134B ubiquitination and activating ER‐phagy, AMFR alleviates progressive fibrosis and cardiac dysfunction by inhibiting the mTORC1 pathway. Consequently, these findings underscore the essential role of AMFR‐driven ER‐phagy in mitigating the progression of fibrotic responses, offering a potential therapeutic target for preventing heart ...
Zhixiang Wang, Kaifan Niu, Wei Liu, Xinyun Wang, Boshen Yang, Taixi Li, Yizhi Chen, Yuanyuan Jin, Yu Chen, Yangyi Lin, Xian Jin   +10 more
wiley   +1 more source

Genetic Impacts on the Structure and Mechanics of Cellulose Made by Bacteria

Advanced Science, EarlyView.
A genetic mutation in a protease of a cellulose‐overproducing evolved bacterium significantly affects the proteome, structure, and mechanical properties of bio‐fabricated cellulose pellicles. By overexpressing synthase proteins that build the cellulose‐forming biological machinery of the cell, the evolved bacterium generates dense, stiff, and strong ...
Julie M. Laurent, Mathias Steinacher, Anton Kan, Maximilian Ritter, Mario Leutert, Siiri Bienz, David Häberlin, Naresh Kumar, André R. Studart   +8 more
wiley   +1 more source

Molecular Diagnosis, Clinical Trial Representation, and Precision Medicine in Minority Patients with Oncogene-Driven Lung Cancer. [PDF]

Cancers (Basel)
Bhatt A, Yone N, Lalla M, Jeon H, Cheng H.   +4 more
europepmc   +1 more source

Griscelli Syndrome: A Case Report from Pakistan, A Review of the Literature, and an Approach to Hematological Disorders Associated With Albinism. [PDF]

Cureus
Afzal M, Ashraf S, Humayun L, Akhtar R, Masood A, Iram S, Imran S.   +6 more
europepmc   +1 more source

White Matter Hyperintensities Precede other Biomarkers in GRN Frontotemporal Dementia

Soltaninejad M, Dadar M, Collins DL, Rajabli R, Venkatraghavan V, Bouzigues A, Russell LL, Foster PH, Ferry-Bolder E, van Swieten JC, Jiskoot LC, Seelaar H, Sanchez-Valle R, Laforce R, Graff C, Galimberti D, Vandenberghe R, de Mendonça A, Tiraboschi P, Santana I, Gerhard A, Levin J, Nacmias B, Otto M, Bertoux M, Lebouvier T, Butler CR, Le Ber I, Finger E, Tartaglia MC, Masellis M, Rowe JB, Synofzik M, Moreno F, Borroni B, Rohrer JD, Iturria Medina Y, Ducharme S, GENFI.   +38 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Spontaneous Mutation of Hemoglobin Lufkin in a White Boy

Journal of Pediatric Hematology/Oncology, 2009
A 10-year-old white boy presented clinically with thalassemia major facies, pallor, jaundice, and hepatomegaly. Investigation revealed the patient has hemoglobin (Hb) Lufkin concurrent with beta(0) thalassemia. DNA sequencing of the beta globin gene confirmed a GGC to a GAC mutation at codon 29 (gly to asp) for Hb Lufkin on the patient and also ...
Paul J. Kurtin, Ding Wen Wu, Peihong Hsu, James D. Hoyer, Ahna M. Blutreich, Gungor Karayalcin   +5 more
openaire   +3 more sources

Migraine with aura and white matter abnormalities: Notch3 mutation [PDF]

Neurology, 2000
The authors report on an Italian family with eight affected members who show autosomal dominant migraine with prolonged visual, sensory, motor, and aphasic aura. These symptoms are associated with white matter abnormalities on brain MRI. All living affected members carry a Notch3 mutation (Arg153Cys) previously reported in cerebral autosomal dominant ...
CERONI, MAURO, POLONI TE, TONIETTI S, FABOZZI D, UGGETTI C, FREDIANI F, SIMONETTI F, MALASPINA A, ALIMONTI D, CELANO M, FERRARI M, CARRERA P.   +11 more
openaire   +2 more sources