Results 41 to 50 of about 4,232 (254)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Journal of Umm Al-Qura University for Language Sciences and Literature, 2022 Ernest Hemingway’s creation of a vilified Jewish character in The Sun Also Rises (1926) has outed him as anti-Semitic. His negative treatment of the Jewish character Robert Cohn can be read as an unpleasant portrait of Jews.
Ammar Aqeeli
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
The Five Refusals of White Supremacy [PDF]
The American Journal of Economics and Sociology, 2018 Abstract This article draws on the work of Charles Mills to posit white supremacy as a global political, economic, and cultural system. Resistance among people of color is, and has always been, widespread. The focus here, however, is on what Mills (1997: 18) describes as the “epistemology of ignorance” among ...
openaire +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Critical Public HealthEpidemiologists have a white supremacy problem. As epidemiologists, we know that a system designed to uphold the privilege of a particular class does not lend itself to health equity.
Jessie Seiler, Nadia N. Abuelezam
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
White Violence and Spectral Blackness in Don DeLillo’s Zero K
Current Objectives of Postgraduate American Studies, 2020 Don DeLillo’s work is often framed as a visionary and ethical reflection on contemporary crises. Such reception redoubles an idea of white American farsightedness and morality that is already embedded in many of DeLillo’s stories—most recently in his ...
Mariya Dimitrova Nikolova
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FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
The Horne Thesis and Cold War Japan
HistoriesGerald Horne’s explication of Cold War-era political history as negotiated white supremacy leads to an enhanced understanding of Japan in the Cold War.
Jason Michael Morgan
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