Results 41 to 50 of about 4,216 (254)
White Supremacy, Lynchings, and Thomas Crawford’s Statue of Freedom
Panorama, 2021 Vivien Green ...
Vivien Green Fryd
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Journal of Umm Al-Qura University for Language Sciences and Literature, 2022 Ernest Hemingway’s creation of a vilified Jewish character in The Sun Also Rises (1926) has outed him as anti-Semitic. His negative treatment of the Jewish character Robert Cohn can be read as an unpleasant portrait of Jews.
Ammar Aqeeli
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Critical Public HealthEpidemiologists have a white supremacy problem. As epidemiologists, we know that a system designed to uphold the privilege of a particular class does not lend itself to health equity.
Jessie Seiler, Nadia N. Abuelezam
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The Five Refusals of White Supremacy [PDF]
The American Journal of Economics and Sociology, 2018 Abstract This article draws on the work of Charles Mills to posit white supremacy as a global political, economic, and cultural system. Resistance among people of color is, and has always been, widespread. The focus here, however, is on what Mills (1997: 18) describes as the “epistemology of ignorance” among ...
openaire +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
The Horne Thesis and Cold War Japan
HistoriesGerald Horne’s explication of Cold War-era political history as negotiated white supremacy leads to an enhanced understanding of Japan in the Cold War.
Jason Michael Morgan
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White Violence and Spectral Blackness in Don DeLillo’s Zero K
Current Objectives of Postgraduate American Studies, 2020 Don DeLillo’s work is often framed as a visionary and ethical reflection on contemporary crises. Such reception redoubles an idea of white American farsightedness and morality that is already embedded in many of DeLillo’s stories—most recently in his ...
Mariya Dimitrova Nikolova
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