Results 41 to 50 of about 101,065 (262)

The relationship between preoperative inflammatory indexes and adherent perinephric fat in laparoscopic partial nephrectomy [PDF]

Scripta Medica
Background/Aim: Partial nephrectomy (PN) is favoured for cT1a renal tumours. However, factors like adherent perinephric fat (APF), linked to prolonged operation time due to chronic inflammation are often overlooked.
Çil Gökhan, Yilmaz Mehmet, Yentur Serhat, Çolakerol Aykut, Canıtez İbrahim Ogulcan   +4 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

A metric on hyperspaces defined by Whitney maps [PDF]

Proceedings of the American Mathematical Society, 1985
For a given continuum X X a new metric on the hyperspace
openaire   +1 more source

Portal Selection for Suture Anchor Placement During Hip Arthroscopic Labral Repair: A Study Based on 3-Dimensional Model Reconstruction

Orthopaedic Journal of Sports Medicine, 2023
Background: Arthroscopic suture repair is the main treatment option for hip labral tears; however, anchor insertion and placement from arthroscopic portals is difficult.
Qi Chen MD, Jiyang Zou MD, Fusheng Wang MD, Kai Qiao MD, Han Li MMed, Weiguo Zhang MD, Kang Tian MD   +6 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Whitney preserving maps on finite graphs

Topology and its Applications, 2011
AbstractFor a Whitney preserving map f:X→G we show the following: (a) If X is arcwise connected and G is a graph which is not a simple closed curve, then f is a homeomorphism; (b) If X is locally connected and G is a simple closed curve, then X is homeomorphic to either the unit interval [0,1], or the unit circle S1.
Espinoza, Benjamin, Illanes, Alejandro
openaire   +1 more source

Central venous pressure dynamics in neonates with hypoxic-ischemic encephalopathy: insights into high mean airway pressure, PPHN, and ECMO management

Frontiers in Pediatrics
IntroductionCentral venous pressure (CVP) monitoring provides valuable insights into hemodynamic changes; however, its application in neonates with hypoxic-ischemic encephalopathy (HIE) undergoing advanced therapies remains underexplored.
Tomonori Kurimoto, Tokuhisa Takuya, Masaya Kibe, Toshio Harumatsu, Hiroshi Ohashi, Tsuyoshi Yamamoto, Eiji Hirakawa   +6 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

An empirical study of drone medical logistics transportation in a multi-campus model of Chinese public hospitals: Real-world data-driven validation of timeliness and application effects.

PLoS ONE
In the real-world application scenario of China's public hospital multi-site operation model, this study systematically evaluates the feasibility, timeliness, and stability of drone-based medical logistics transportation between hospital campuses ...
Xingbo Long, Min Huang, Xiankai Xie, Yanxin Wang, Xiaojiang Yu, Wei Zhou, Bo Hu   +6 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source