Results 71 to 80 of about 11,763,099 (219)

VDAC1 Upregulation Induces Hyperexcitability of Nociceptive Sensory Neurons Via Enhanced Mitochondrial Atp Efflux in Neuropathic Pain

Advanced Science, EarlyView.
The mechanism diagram of VDAC1 mediating neuronal excitability and neuropathic pain. Briefly, VDAC1 is expressed in DRG neurons and is upregulated following CCI‐induced neuropathic pain. This upregulation enhances ATP transport from mitochondria to the cytoplasm in sensory neurons, leading to increased neuronal excitability and pain behavior.
Fengrun Sun, Ning Yu, Liang Yu, Xiaofen Tian, Yujia Ma, Yikuan Xie, Tao Wang, Chao Ma   +7 more
wiley   +1 more source

Best Practice Guidelines for the Management of Patients with Post-Stroke Spasticity: A Modified Scoping Review

Toxins
This article aims to provide a concise overview of the best available evidence for managing post-stroke spasticity. A modified scoping review, conducted following the PRISMA guidelines and the PRISMA Extension for Scoping Reviews (PRISMA-ScR), involved ...
Areerat Suputtitada, Supattana Chatromyen, Carl P. C. Chen, David M. Simpson   +3 more
doaj   +1 more source

Highly Flexible and Conformable ZnO/FeGa Magnetoelectric Heterostructures for Skin wound Healing

Advanced Science, EarlyView.
The magnetic field‐induced electric field generated by a highly flexile ZnO(piezoelectric)/FeGa(magnetostrictive) magnetoelectric heterostructure embedded in the low Young's modulus elastomer PDMS has been used to stimulate the wound healing processes.
Filippos Perdikos, Laia Bagur, Cristina Vaca, Aritz Lafuente, Joaquin Llacer‐Wintle, Bojan Ambrožič, Christina Stefani, Minsoo Kim, Goran Dražić, Darja Lisjak, Jordi Sort, Xiang‐Zhong Chen, Maria Jose Esplandiu, Salvador Pané, Carme Nogués, Josep Nogués, Andreu Blanquer, Borja Sepúlveda   +17 more
wiley   +1 more source

Corrigendum: Position statement and updated international guideline for safe and effective whole-body electromyostimulation training-the need for common sense in WB-EMS application

Frontiers in Physiology, 2023
Wolfgang Kemmler, Michael Fröhlich, Oliver Ludwig, Christoph Eifler, Simon Von Stengel, Sebastian Willert, Marc Teschler, Anja Weissenfels, Heinz Kleinöder, Florian Micke, Nicolas Wirtz, Christoph Zinner, Andre Filipovic, Bernd Wegener, Joshua Berger, Alexandre Evangelista, Stefano D’ottavio, Jaskanwal Deep Singh Sara, Amir Lerman, Unai A. Perez De Arrilucea Le Floc’h, Abraham Carle-Calo, Angel Guitierrez, Francisco J. Amaro-Gahete, Francisco J. Amaro-Gahete, Francisco J. Amaro-Gahete, Francisco J. Amaro-Gahete   +25 more
doaj   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Near-InfraRed Spectroscopy Provides a Reproducible Estimate of Muscle Aerobic Capacity, but Not Whole-Body Aerobic Power

Sensors
Near-infrared spectroscopy (NIRS) during repeated limb occlusions is a noninvasive tool for assessing muscle oxidative capacity. However, the method’s reliability and validity remain under investigation.
Tomas Venckunas, Andrius Satas, Marius Brazaitis, Nerijus Eimantas, Saule Sipaviciene, Sigitas Kamandulis   +5 more
doaj   +1 more source

Closed‐Loop Decoding and Intervention of Pain: A Novel BMI Strategy Integrating θ‐Band Detection and Mechano‐Electro‐Biological Coupled Hydrogels

Advanced Science, EarlyView.
A closed‐loop brain–machine interface with a PFAPT hydrogel electrode identifies prefrontal θ‐band as a neuropathic pain biomarker. The hydrogel enables stable 28 d ECoG recording and delivers θ‐triggered cortical stimulation, alleviating pain and affective behaviors in rats via bidirectional regulation of inflammation and central sensitization ...
Yun Ji, Tao Li, Guoqiang Lei, Huichun Luo, Xiuqian Guo, Jiao Xiang, Tao Shi, Weitang Liu, Yuxin Zhang, Xiaoyu Liao, Shutao Zhao, Jiayun Wu, Wangao Zhang, Wenhui Liu, Chuanglong He, Shuo Chen, Tao Wu, Ke Ma   +17 more
wiley   +1 more source

High-intensity interval training using electrical stimulation ameliorates muscle fatigue in chronic kidney disease-related cachexia by restoring mitochondrial respiratory dysfunction

Frontiers in Physiology
BackgroundExercise, especially high-intensity interval training (HIIT), can increase mitochondrial respiratory capacity and enhance muscular endurance, but its systemic burden makes it difficult to safely and continuously prescribe for patients with ...
Hiroyori Fusagawa, Hiroyori Fusagawa, Tatsuya Sato, Tatsuya Sato, Takashi Yamada, Azuma Naito, Nao Tokuda, Nao Yamauchi, Nobutoshi Ichise, Toshifumi Ogawa, Toshifumi Ogawa, Takuro Karaushi, Atsushi Teramoto, Noritsugu Tohse   +13 more
doaj   +1 more source

Muscle wasting and function after muscle activation and early protocol‐based physiotherapy: an explorative trial

Journal of Cachexia, Sarcopenia and Muscle, 2019
Background Early mobilization improves physical independency of critically ill patients at hospital discharge in a general intensive care unit (ICU)‐cohort.
Tobias Wollersheim, Julius J. Grunow, Niklas M. Carbon, Kurt Haas, Johannes Malleike, Sara F. Ramme, Joanna Schneider, Claudia D. Spies, Sven Märdian, Knut Mai, Simone Spuler, Jens Fielitz, Steffen Weber‐Carstens   +12 more
doaj   +1 more source

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source