Results 131 to 140 of about 552,282 (159)
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JAMA, 2011
THE PAST 60 YEARS HAVE WITNESSED REMARKABLE progress in genetics and genomics from the description of the DNA double helix by Watson and Crick to the release of the first draft sequence of the human genome in 2001 and the successful completion of the human genome project in 2003.
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THE PAST 60 YEARS HAVE WITNESSED REMARKABLE progress in genetics and genomics from the description of the DNA double helix by Watson and Crick to the release of the first draft sequence of the human genome in 2001 and the successful completion of the human genome project in 2003.
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Whole exome and whole genome sequencing
Current Opinion in Pediatrics, 2011The purpose of this review is to describe the new DNA sequencing technologies referred to as next-generation sequencing (NGS). These new methods are becoming central to research in human disease and are starting to be used in routine clinical care.Advances in instrumentation have dramatically reduced the cost of DNA sequencing.
David, Bick, David, Dimmock
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Advances in Whole Genome Sequencing Technology
Current Pharmaceutical Biotechnology, 2011Sanger sequencing revolutionized the field of genetics by becoming the standard approach to appraise a given region of the genome at base-level resolution. However, the relatively recent need to sequence entire genomes has driven innovative developments within the market-place to allow for sequencing technology to be faster, cheaper and more accurate ...
Jianhua, Zhao, Struan F A, Grant
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Preparation of Cryptosporidium for Whole-Genome Sequencing
The application of whole-genome sequencing (WGS) to Cryptosporidium has been challenged by the relatively small numbers of oocysts present in feces and lack of suitable culture systems to generate sufficient DNA that is required. Here, we provide a method for the preparation of sufficient, high-quality Cryptosporidium DNA for WGS from feces ...Guy, Robinson, Rachel M, Chalmers
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Clinical interpretation of whole-genome and whole-transcriptome sequencing for precision oncology
Seminars in Cancer Biology, 2022Anna Schuh +2 more
exaly