Results 61 to 70 of about 3,634,772 (267)
Entering into a Community-University Collaboration
Journal of Agriculture, Food Systems, and Community Development, 2018 First paragraph: When asked to tell the story of how and why I was invited and decided to join the Food Dignity research project, I found myself traveling back over a long road full of unexpected turns, bumps, discoveries, and delights. And as I began
E. Jemila Sequeira
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Relation Between Whole and Part in Leibnitz Philosophy
Journal of Philosophical Investigations, 2014 Here, on the one hand, regarding to the fundamental idea of Leibniz’s philosophy, namely, «Substance”, we will try to study the different kinds of whole and part and their relationship.
Zahra Nouri Sangdehi; Hourieh Bakoui Katrimi
doaj
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Parts and wholes in language. The case of semantic underspecification
Gestalt TheoryThe issue of the relations between parts and wholes is perhaps one of the most important theoretical issues of linguistic structuralism, to the point that it can be considered as a defining element of this very paradigm.
Cigana Lorenzo
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Engineering ProceedingsVirtual lifetime estimation is growing in importance, as replacing physical tests by simulations leads to cost reductions in the development of microelectronics assemblies.
Yashveer Dunputh +5 more
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