Results 81 to 90 of about 12,108,613 (278)

Entering into a Community-University Collaboration

open access: yesJournal of Agriculture, Food Systems, and Community Development, 2018
First paragraph: When asked to tell the story of how and why I was invited and decided to join the Food Dignity research project, I found myself traveling back over a long road full of unexpected turns, bumps, discoveries, and delights. And as I began
E. Jemila Sequeira
doaj   +1 more source

Whole body cleaning agent containing N-acyltaurate [PDF]

open access: yes, 1992
The subject invention relates to a human cleansing agent particularly suitable for use in long duration spaceflight and to a method of bathing with the agent.
Lentsch, Steven E.
core   +1 more source

Using the Whole School, Whole Community, Whole Child Model: Implications for Practice

open access: yesJournal of School Health, 2015
ABSTRACTBACKGROUNDSchools, school districts, and communities seeking to implement the Whole School, Whole Community, Whole Child (WSCC) model should carefully and deliberately select planning, implementation, and evaluation strategies.METHODSIn this article, we identify strategies, steps, and resources within each phase that can be integrated into ...
Rooney, Laura E   +2 more
openaire   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Nature, Science, Bayes' Theorem, and the Whole of Reality [PDF]

open access: yes, 2015
A fundamental problem in science is how to make logical inferences from scientific data. Mere data does not suffice since additional information is necessary to select a domain of models or hypotheses and thus determine the likelihood of each model or ...
Alexanian, Moorad
core  

PSACNN: Pulse Sequence Adaptive Fast Whole Brain Segmentation

open access: yes, 2019
With the advent of convolutional neural networks~(CNN), supervised learning methods are increasingly being used for whole brain segmentation. However, a large, manually annotated training dataset of labeled brain images required to train such supervised ...
Fischl, Bruce   +4 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Review of Finite Element Vehicle Interior Acoustic Simulations Including Porous Materials

open access: yesActa Technica Jaurinensis, 2019
Recent trends in vehicle engineering require manufacturers to develop products with highly refined noise, vibration and harshness levels. The use of trim elements, which can be described as Poroelastic materials (PEM), are key to achieve quiet interiors.
János Csaba Kun, Daniel Feszty
doaj   +1 more source

Whole-school mental health promotion in Australia [PDF]

open access: yes, 2011
Although there is increasing recognition internationally of the significance of social and emotional health and wellbeing for the healthy development of young people, the levels of support that governments provide for mental health policy and programme
Askell-Williams, Helen   +2 more
core  

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