Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec +5 more
wiley +1 more source
Prehospital whole-blood transfusion in two countries: comparison of patient characteristics in Sweden and the Northeastern United States. [PDF]
Backstrom D +8 more
europepmc +1 more source
The DA/VTP‐NBs selectively recognized cardiac ECs damaged by DIC and achieved cell‐level targeted imaging. Then US‐triggered controlled release successfully enabled the release of DAPA within the DA/VTP‐NBs at the site of injury. This precise on‐demand drug release approach amplifies a series of localized therapeutic effects through the mtDNA‐mediated ...
Jun Zhang +8 more
wiley +1 more source
Comparison of automated and manual mRNA enrichment to automated rRNA depletion for whole-blood RNA-sequencing. [PDF]
Awany D +7 more
europepmc +1 more source
Paper-Based Device for the Colorimetric Determination of Glucose in Whole-Blood Samples Using a Smartphone. [PDF]
Boga LBA +4 more
europepmc +1 more source
Under Pressure: Rapid Infusion of Stored Whole Blood Alters Coagulation Parameters. [PDF]
Becker ER +6 more
europepmc +1 more source
Correction to: Comparison of whole blood on filter strips with serum for avian influenza virus antibody detection in wild birds. [PDF]
europepmc +1 more source
Plasticity of the fatty acid whole blood lipidome in the progression of canine periodontal disease: a pilot study. [PDF]
Silva C +8 more
europepmc +1 more source
Diagnostic potential of GLP recombinant antigens in whole blood assays for Leishmania infantum infection. [PDF]
Ibarra-Meneses AV +11 more
europepmc +1 more source

