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Whole-Blood Model

2003
Neisseria meningitidis is an obligate human pathogen. When it interacts with the host, it can establish a commensal relationship or can, on a minority of occasions, invade and cause systemic disease. Protection against systemic disease, particularly for serogroup A and C infections, has been equated with the presence of bactericidal antibody directed ...
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Determination of Hexachlorophene in Whole Blood

Journal of Pharmaceutical Sciences, 1969
An efficient method for the quantitative recovery of hexachlorophene from whole blood is described. It can be applied to both human and animal blood, and utilizes an extraction procedure followed by electron-capture detection with gas chromatography. Problems encountered in the reproducible isolation of hexachlorophene are discussed.
P J, Porcaro, P, Shubiak, M, Manowitz
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Whole blood for old blood: Use of whole blood for resuscitation in older trauma patients

Injury
Older patients are expected to comprise 40 % of trauma admissions in the next 30 years. The use of whole blood (WB) has shown promise in improving mortality while lowering the utilization of blood products. However, the use of WB in older trauma patients has not been examined.
Gregory R. Stettler   +8 more
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Platelets and whole blood coagulation

Perfusion, 2000
In our early work in developing activated clotting time (ACT) assays, it became apparent that changes occurred in coagulation times as a whole blood sample aged (0-6 h). Subsequent studies showed that the coagulation parameters of plasma obtained from the samples remained stable during this time frame.
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Whole Blood Assay: Thromboelastometry

2016
Thromboelastometry (ROTEM®) is an advancement of the classical thrombelastography (TEG), first described by Hellmut Hartert in 1948. Since then, several technical enhancements made the device more robust and user-friendly, reduced intra- and inter-operator variability, and improved the diagnostic performance.
Görlinger, Klaus   +3 more
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Whole blood viscosity in preeclampsia

American Journal of Obstetrics and Gynecology, 1982
Whole blood viscosity was measured in 41 patients with preeclampsia and in 51 normotensive control subjects. The mean viscosity in the preeclamptic group had a highly significant elevation (t = 9.752, p less than 0.001, at a shear rate of 0.1 sec-1 and t = 4.223, p less than 0.001, at a shear rate of 100 sec-1).
J B, Hobbs   +6 more
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Measurement of Whole Blood Osmolality

American Journal of Clinical Pathology, 1982
When plasma osmolality exceeds 350 milliosmoles per kilogram of plasma water during cardiopulmonary resuscitation, a disproportionate increase in mortality is observed. The increase of plasma osmolality is in part related to the administration of sodium bicarbonate.
M H, Weil, S, Michaels, D, Klein
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WHOLE BLOOD AND CITRATED BLOOD

Journal of the American Medical Association, 1945
To the Editor:— Dr. Scannell's communication inThe Journal, June 23, attempts to correct what he considers to be an error and brings to light a skeleton which most of us thought had been securely and permanently locked away in a closet. The term "whole blood" has been most frequently applied to blood obtained from so-called live donors and ...
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Whole Blood Aggregometry in Mice

Current Protocols
AbstractAggregometry plays a crucial role in both clinical diagnostics and research within hematology, serving as a fundamental tool for understanding platelet function and its implications in physiological and pathological processes. In research, aggregometry provides insights into platelet aggregation dynamics and aids in understanding the underlying
Siobhan Branfield   +3 more
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Whole Blood Platelet Aggregometry

2017
Light transmittance aggregometry is the historical reference method for platelet function testing and continues to be used extensively. Whole blood impedance lumiaggregometry represents an updated methodology that provides for simplified specimen management, an assay milieu that replicates in vivo platelet activation conditions, improved ...
George A, Fritsma, David L, McGlasson
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