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A whole genome simulator of prokaryote genome evolution
Proceedings of the 2nd ACM Conference on Bioinformatics, Computational Biology and Biomedicine, 2011With the increase of the number of available prokaryotic genomes, studies focusing on the higher level evolutionary events, including the evolution of whole genomes, are now possible. Simulated datasets are essential components in both the development and evaluation stages for all evolutionary studies.
Kuan Yang, João Carlos Setubal
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WHOLE GENOME IDENTITY-BY-DESCENT DETERMINATION
Journal of Bioinformatics and Computational Biology, 2013High-throughput single nucleotide polymorphism genotyping assays conveniently produce genotype data for genome-wide genetic linkage and association studies. For pedigree datasets, the unphased genotype data is used to infer the haplotypes for individuals, according to Mendelian inheritance rules.
Hadi Sabaa +5 more
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The Role of Whole Genome and Whole Exome Sequencing in Preventive Genomic Sequencing Programs
The American Journal of Bioethics, 2015The target article by Lazaro-Munoz and colleagues (2015) proposes policy recommendations on opt-in/opt-out strategies for the development of population-based preventive genomic sequencing programs ...
Gabrielle, Bertier +2 more
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Current Opinion in Genetics & Development, 2006
DNA sequencing can be used to gain important information on genes, genetic variation and gene function for biological and medical studies. The growing collection of publicly available reference genome sequences will underpin a new era of whole genome re-sequencing, but sequencing costs need to fall and throughput needs to rise by several orders of ...
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DNA sequencing can be used to gain important information on genes, genetic variation and gene function for biological and medical studies. The growing collection of publicly available reference genome sequences will underpin a new era of whole genome re-sequencing, but sequencing costs need to fall and throughput needs to rise by several orders of ...
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Whole-Genome Sequencing in Pharmacogenetics
Pharmacogenomics, 2013on clinical disease prediction, and remarking on the problem of ‘missing heritability’ of risk for common diseases unaccounted for by common variants [1], the arena of pharmacogenetics was often singled out as an exception [2]. GWAS of drug response traits are quite exceptional in having provided a number of clinically significant genetic predictors of
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WGA(whole genome association, whole genome assembly, whole genome array)
2008openaire +1 more source