Results 111 to 120 of about 533,077 (310)

Supplementary Figure S2 from Whole-Genome Sequencing of Asian Lung Cancers: Second-Hand Smoke Unlikely to Be Responsible for Higher Incidence of Lung Cancer among Asian Never-Smokers

, 2023
Vidhya G. Krishnan, Philip J. Ebert, Jason C. Ting, Elaine Hsuen Lim, Swee-Seong Wong, Audrey S.M. Teo, Yong Yue, Hui-Hoon Chua, Xiwen Ma, Gary S.L. Loh, Yuhao Lin, Joanna Tan, Yu Kun, Shenli Zhang, Christoph Reinhard, Daniel S.W. Tan, Brock A. Peters, Stephen E. Lincoln, Dennis G. Ballinger, Jason M. Laramie, Geoffrey B. Nilsen, Thomas D. Barber, Patrick Tan, Axel M. Hillmer, Pauline C. Ng   +24 more
openalex   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Experimental Evolution of Enhanced Growth by Bacillus subtilis at Low Atmospheric Pressure: Genomic Changes Revealed by Whole-Genome Sequencing [PDF]

, 2015
Samantha M. Waters, Daniel R. Zeigler, Wayne L. Nicholson   +2 more
openalex   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Whole Genome Sequencing of Mycobacterium tuberculosis Clinical Isolates From India Reveals Genetic Heterogeneity and Region-Specific Variations That Might Affect Drug Susceptibility

, 2019
Jayshree Advani, Renu Verma, Oishi Chatterjee, Praveen K. Pachouri, Prashant Upadhyay, Rajesh K. Singh, Jitendra Singh Yadav, Farah Naaz, Raju Ravikumar, Shashidhar Buggi, Mrutyunjay Suar, Umesh Gupta, Akhilesh Pandey, Devendra Singh Chauhan, Srikanth Tripathy, Harsha Gowda, Thottethodi Subrahmanya Keshava Prasad   +16 more
openalex   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Marching toward 100% whole genome sequencing

Frontiers in Genetics, 2016
Yih-Horng eShiao
doaj   +1 more source

Whole Genome Sequencing and Antimicrobial Resistance of Staphylococcus aureus from Surgical Site Infections in Ghana [PDF]

, 2021
Beverly Egyir, Jeannette Bentum, Naiki Attram, Anne A. Fox, Noah Obeng‐Nkrumah, Appiah-Korang Labi, Eric Behene, Selassie Kumordjie, Clara Yeboah, Bright Agbodzi, Ronald Essah Bentil, Rhodalyn Tagoe, Blessing Kofi Adu Tabi, Felicia Owusu, Nicholas T. K. D. Dayie, Eric S. Donkor, Josephine Nsaful, Kwaku Asah‐Opoku, Edward Owusu Nyarko, Edward Asumanu, Anders Rhod Larsen, David M. Wolfe, Andrew G. Letizia   +22 more
openalex   +1 more source