Results 251 to 260 of about 533,077 (310)

Comprehensive assessment of whole-genome sequencing-based variant calling pipelines in monozygotic twins. [PDF]

Brief Bioinform
Tan C, Sun W, Yu J, Fu J, Ming C, Liu X.
europepmc   +1 more source

A pragmatic pipeline for drug resistance and lineage identification in Mycobacterium tuberculosis using whole genome sequencing

Linzy Elton, Alp Aydin, Neil G. Stoker, Sylvia Rofael, Letícia Muraro Wildner, Jabar Babatunde Pacome Agbo Achimi Abdul, John Tembo, Muzamil Mahdi Abdel Hamid, Mfoutou Mapanguy Claujens Chastel, Julio Ortiz Canseco, Ronan Doyle, Giovanni Satta, Justin O’Grady, Adam A. Witney, Francine Ntoumi, Alimuddin Zumla, Timothy D. McHugh   +16 more
openalex   +1 more source

Regulating Tumor Metabolic Reprogramming with Biomimetic Co‐Delivery of Simvastatin and Kynureninase for Immunotherapy

Advanced Science, EarlyView.
After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin, Shengcai Yang, Zengguang Liu, Songchen Zhao, Siyu Sun, Ziling Liu, Quanshun Li   +6 more
wiley   +1 more source

Machine learning-based discovery of informative SNPs for population assignment through whole genome sequencing. [PDF]

BMC Genomics
Liang H, He Y, Si J, Su X, Wang X, Mao H, Zhang Y.   +6 more
europepmc   +1 more source

Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen

Advanced Science, EarlyView.
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang, Qing Wu, Hao‐Long Zeng, Yin Shen, Hong‐Han Zhang, Jun Gong, Qi Zhang, Jia‐Zhao Xie, Da‐Wei Ye, Zi‐Yong Sun, Zhong‐Chun Liu, Li‐Ming Cheng, Di Li   +12 more
wiley   +1 more source

Whole-genome sequencing reveals individual and cohort level insights into chromosome 9p syndromes. [PDF]

Genome Med
Wang Y, Sams EI, Slaugh R, Crocker S, Hurtado EC, Tracy S, Hou YC, Markovic C, Valle K, Tate V, Belhassan K, Appelbaum E, Akinwe T, Starosta RT, Cao Y, Neilson A, Liu Y, Jensen N, Ghasemi R, Lindsay T, Manuel J, Couteranis S, Kremitzki M, Ustanik J, Antonacci T, Ng JK, Emory A, Metz L, DeLuca T, Lyons KN, Sinnwell T, Thomeczek B, Wang K, Sisneros N, Muraleedharan M, Kethireddy A, Corbo M, Gowda H, King KA, Gurnett CA, Dutcher SK, Gooch C, Li YE, Mitchell MW, Peterson KA, Horani A, Rosenfeld JA, Bi W, Stankiewicz P, Chao HT, Posey JE, Grochowski CM, Dardas Z, Puffenberger EG, Pearson CE, Kooy F, Annear D, Innes AM, Heinz M, Head R, Fulton R, Toutain S, 9P-ARCH, Antonacci-Fulton L, Cui X, Mitra RD, Cole FS, Neidich J, Dickson PI, Milbrandt J, Turner TN.   +70 more
europepmc   +1 more source

Application of whole genome sequencing for carrier and diagnostic assessment of spinal muscular atrophy in Taiwan. [PDF]

NPJ Genom Med
Lin LL, Chien PM, Hsiao TH, Ye HY, Liu SH, Ko TM, Huang CH, Chen PL, Chen WC, Chou YT, Wu CS, Chen HH, Chien YH, Hsu JS.   +13 more
europepmc   +1 more source

Whole-genome sequencing for every newborn in the UK: promise and practicalities. [PDF]

EClinicalMedicine
eClinicalMedicine.
europepmc   +1 more source

Lenticulostriate vasculopathy in newborns: whole genome sequencing data analysis. [PDF]

Front Pediatr
Dauengauer-Kirlienė S, Pranauskas D, Singh Y, Kučinskas V, Urnikytė A.   +4 more
europepmc   +1 more source

Revisiting classical <i>Escherichia coli</i> cell division mutants by whole-genome sequencing. [PDF]

Microb Genom
Dahdouh E, García-Pérez I, Reyes-Zuñagua DS, Mingorance J, Vicente M.   +4 more
europepmc   +1 more source