Results 271 to 280 of about 533,077 (310)
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Evaluation of Whole Genome Sequencing Data
2019Whole genome sequencing (WGS) can provide comprehensive insights into the genetic makeup of lymphomas. Here we describe a selection of methods for the analysis of WGS data, including alignment, identification of different classes of genomic variants, the identification of driver mutations, and the identification of mutational signatures.
Hübschmann, Daniel, Schlesner, Matthias
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Whole-Genome Sequencing in Pharmacogenetics
Pharmacogenomics, 2013on clinical disease prediction, and remarking on the problem of ‘missing heritability’ of risk for common diseases unaccounted for by common variants [1], the arena of pharmacogenetics was often singled out as an exception [2]. GWAS of drug response traits are quite exceptional in having provided a number of clinically significant genetic predictors of
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Whole-Genome Sequencing of Unculturable Bacterium Using Whole-Genome Amplification
2011More than 99% of microorganisms on the earth are unculturable with known culturing techniques. The emergence of metagenomics with high-throughput sequencing technologies has enabled researchers to capture a comprehensive view of a complex bacterial community which comprises both culturable and unculturable species.
Yuichi Hongoh, Toyoda, A.
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Computing in Science & Engineering, 1999
Computation is integrally and powerfully involved with the DNA sequencing technology that promises to reveal the complete human DNA sequence in the next several years. After introducing the latest DNA sequencing methods, this article describes three current approaches for completing the sequencing.
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Computation is integrally and powerfully involved with the DNA sequencing technology that promises to reveal the complete human DNA sequence in the next several years. After introducing the latest DNA sequencing methods, this article describes three current approaches for completing the sequencing.
openaire +1 more source
Whole-Genome Sequencing in Personalized Therapeutics
Clinical Pharmacology & Therapeutics, 2012Eleven years since the initial drafts of the human genome were published, we have begun to see the first examples of the application of whole-genome sequencing to personalized diagnosis and therapeutics. The exponential decline in sequencing costs and the constant improvement in these technologies promise to further advance the use of a patient's full ...
P, Cordero, E A, Ashley
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Whole-Genome Sequencing Recommendations
2016Recent technological developments have revolutionized the way we perform genetic analyses. In particular whole-genome sequencing provides access to the entire genetic makeup of an individual, and it is now an affordable approach for many research groups. As a consequence genome sequencing is pervading many fields of biological research.
Toni Gabaldón, Tyler S. Alioto
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Cancer Whole-Genome Sequencing
The Journal of Molecular Diagnostics, 2021Andrew C. Nelson, Sophia L. Yohe
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Treatment of muscle‐invasive and advanced bladder cancer in 2020
Ca-A Cancer Journal for Clinicians, 2020Vaibhav G Patel +2 more
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