Whole genome sequencing in Mycobacterium tuberculosis [PDF]
Fighting the emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) requires a proper and personalized use of new antitubercular drugs. To achieve this goal, the sensitivity profile to antitubercular drug should be available in a short-time and results should be highly reliable be used for patient-care.
Andrea Spitaleri+3 more
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Whole-genome sequencing of Klebsiella pneumoniae isolates to track strain progression in a single patient with recurrent urinary tract infection [PDF]
Klebsiella pneumoniae is an important uropathogen that increasingly harbors broad-spectrum antibiotic resistance determinants. Evidence suggests that some same-strain recurrences in women with frequent urinary tract infections (UTIs) may emanate from a ...
Minx, Patrick J+3 more
core +5 more sources
Toward 959 nematode genomes [PDF]
The sequencing of the complete genome of the nematode Caenorhabditis elegans was a landmark achievement and ushered in a new era of whole-organism, systems analyses of the biology of this powerful model organism. The success of the C.
Blaxter, M+3 more
core +1 more source
Virilizer (Vir), first isolated from Drosophila melanogaster, plays a role in sex determination. In humans, its homologue and METTL3 are involved in N6-adenosine methylation (m6A) writing. As m6A of mRNA is an important process in most eukaryotes, it is very important to understand its role and the status of factors accompanying this modification ...
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Whole Genome Sequencing and the Zygomycota [PDF]
Copyright: © 2014 Gryganskyi AP, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Andrii P. Gryganskyi, Anna Muszewska
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Cronobacter, the emergent bacterial pathogen Enterobacter sakazakii comes of age; MLST and whole genome sequence analysis [PDF]
Background: Following the association of Cronobacter spp. to several publicized fatal outbreaks in neonatal intensive care units of meningitis and necrotising enterocolitis, the World Health Organization (WHO) in 2004 requested the establishment of a ...
Dickins, B, Forsythe, SJ, Jolley, KA
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Draft Genome Sequences of Pseudomonas aeruginosa Strain PS3 and Citrobacter freundii Strain SA79 Obtained from a Wound DressingAssociated Biofilm [PDF]
Two isolates, one from the genus Pseudomonas and the second from Citrobacter, were isolated from a wound dressing-associated biofilm. Following whole-genome sequencing, the two isolates presented genes encoding for resistance to antibiotics and those ...
Akbar, Sirwan+2 more
core +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
Whole Genome Sequence of a Turkish Individual
Although whole human genome sequencing can be done with readily available technical and financial resources, the need for detailed analyses of genomes of certain populations still exists. Here we present, for the first time, sequencing and analysis of a Turkish human genome.
Dogan, Haluk, Can, Handan, Otu, Hasan H.
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Whole genome sequencing in families with oligodontia
AbstractBackground/ObjectivesTooth agenesis (TA) is among the most common malformations in humans. Although several causative mutations have been described, the genetic cause often remains elusive. Here, we test whether whole genome sequencing (WGS) could bridge this diagnostic gap.MethodsIn four families with TA, we assessed the dental phenotype using
Janna Mitscherling+6 more
openaire +3 more sources