Results 21 to 30 of about 905,467 (298)

A Distributed Whole Genome Sequencing Benchmark Study

Frontiers in Genetics, 2020
Population sequencing often requires collaboration across a distributed network of sequencing centers for the timely processing of thousands of samples.
Richard D. Corbett, Robert Eveleigh, Joe Whitney, Namrata Barai, Mathieu Bourgey, Eric Chuah, Joanne Johnson, Richard A. Moore, Neda Moradin, Karen L. Mungall, Sergio Pereira, Miriam S. Reuter, Bhooma Thiruvahindrapuram, Richard F. Wintle, Jiannis Ragoussis, Lisa J. Strug, Jo-Anne Herbrick, Naveed Aziz, Steven J. M. Jones, Mark Lathrop, Stephen W. Scherer, Alfredo Staffa, Andrew J. Mungall   +22 more
doaj   +1 more source

Genomic data of an environmental Escherichia coli isolate shows high resemblance to E. coli K-12 reference strain MG1655

Data in Brief, 2021
Escherichia coli species exhibits a high genomic diversification from evolution, mobile genetic elements and recombination. An environmental E. coli isolate, ‘JHI_5025’ from a crop trial appeared to be clonally related to the historical reference isolate
Nicola Holden
doaj   +1 more source

Genomic dissection of the 1994 Cronobacter sakazakii outbreak in a French neonatal intensive care unit [PDF]

, 2015
Background: Cronobacter sakazakii is a member of the genus Cronobacter that has frequently been isolated from powdered infant formula (PIF) and linked with rare but fatal neonatal infections such as meningitis and necrotising enterocolitis.
Dickins, B, Farbos, A, Forsythe, S, Masood, N, McNally, A, Moore, K, Paszkiewicz, K   +6 more
core   +2 more sources

Whole-Genome Sequencing in Cancer [PDF]

Cold Spring Harbor Perspectives in Medicine, 2018
Genome sequencing of cancer has fundamentally advanced our understanding of the underlying biology of this disease, and more recently has provided approaches to characterize and monitor tumors in the clinic, guiding and evaluating treatment. Although cancer research is relying more on whole-genome characterization, the clinical application of genomics ...
Eric Y, Zhao, Martin, Jones, Steven J M, Jones   +2 more
openaire   +2 more sources

Whole-genome sequencing and the clinician: a tale of two cities [PDF]

, 2014
Clinicians are faced with unprecedented opportunities to identify the genetic aetiologies of hitherto molecularly uncharacterised conditions via the use of high-throughput sequencing.
A. R. Foley, Dickens, Dubowitz, F. Muntoni, Foley, Gualandi, J. He, J. Kim, Jöbsis, Jöbsis, Kim, Lupski, M. G. Hanna, Mercuri, Mercuri, Morrow, N. M. Pearson, Pace, Pan, Phimister, R. D. S. Pitceathly, Straub   +21 more
core   +2 more sources

Human Whole-Genome Shotgun Sequencing [PDF]

Genome Research, 1997
Large-scale sequencing of the human genome is now under way (Boguski et al. 1996; Marshall and Pennisi 1996). Although at the beginning of the Genome Project, many doubted the scientific value of sequencing the entire human genome, these doubts have evaporated almost entirely (Gibbs 1995; Olson 1995).
J L, Weber, E W, Myers
openaire   +2 more sources

Whole-genome sequencing of Klebsiella pneumoniae isolates to track strain progression in a single patient with recurrent urinary tract infection [PDF]

, 2019
Klebsiella pneumoniae is an important uropathogen that increasingly harbors broad-spectrum antibiotic resistance determinants. Evidence suggests that some same-strain recurrences in women with frequent urinary tract infections (UTIs) may emanate from a ...
Minx, Patrick J, Rosen, David A, Wylie, Kristine M, Wylie, Todd N   +3 more
core   +5 more sources

Whole genome sequencing analysis of Plasmodium vivax using whole genome capture

BMC Genomics, 2012
Background Malaria caused by Plasmodium vivax is an experimentally neglected severe disease with a substantial burden on human health. Because of technical limitations, little is known about the biology of this important human pathogen.
Bright A, Tewhey Ryan, Abeles Shira, Chuquiyauri Raul, Llanos-Cuentas Alejandro, Ferreira Marcelo U, Schork Nicholas J, Vinetz Joseph M, Winzeler Elizabeth A   +8 more
doaj   +1 more source

Draft Genome Sequences of Pseudomonas aeruginosa Strain PS3 and Citrobacter freundii Strain SA79 Obtained from a Wound DressingAssociated Biofilm [PDF]

, 2015
Two isolates, one from the genus Pseudomonas and the second from Citrobacter, were isolated from a wound dressing-associated biofilm. Following whole-genome sequencing, the two isolates presented genes encoding for resistance to antibiotics and those ...
Akbar, Sirwan, Humphreys, Paul, Rout, Simon   +2 more
core   +1 more source

Salmonella Serotyping Using Whole Genome Sequencing

Frontiers in Microbiology, 2018
Until recently, traditional serology and the Kauffmann White Scheme (KWS) have been the gold standard for Salmonella serotyping. Whole Genome Sequencing (WGS) has now emerged as an alternative in this field.
George M. Ibrahim, Paul M. Morin
doaj   +1 more source