Results 21 to 30 of about 567,748 (308)

Whole genome sequencing analysis of Plasmodium vivax using whole genome capture

BMC Genomics, 2012
Background Malaria caused by Plasmodium vivax is an experimentally neglected severe disease with a substantial burden on human health. Because of technical limitations, little is known about the biology of this important human pathogen.
Bright A, Tewhey Ryan, Abeles Shira, Chuquiyauri Raul, Llanos-Cuentas Alejandro, Ferreira Marcelo U, Schork Nicholas J, Vinetz Joseph M, Winzeler Elizabeth A   +8 more
doaj   +1 more source

Salmonella Serotyping Using Whole Genome Sequencing

Frontiers in Microbiology, 2018
Until recently, traditional serology and the Kauffmann White Scheme (KWS) have been the gold standard for Salmonella serotyping. Whole Genome Sequencing (WGS) has now emerged as an alternative in this field.
George M. Ibrahim, Paul M. Morin
doaj   +1 more source

Rapid whole genome sequencing methods for RNA viruses

Frontiers in Microbiology, 2023
RNA viruses are the etiological agents of many infectious diseases. Since RNA viruses are error-prone during genome replication, rapid, accurate and economical whole RNA viral genome sequence determination is highly demanded.
Masayasu Misu, Masayasu Misu, Tomoki Yoshikawa, Satoko Sugimoto, Yuki Takamatsu, Takeshi Kurosu, Yukiteru Ouji, Masahide Yoshikawa, Masayuki Shimojima, Hideki Ebihara, Masayuki Saijo   +10 more
doaj   +1 more source

Complete mitochondrial genomes of Culicoides brevitarsis and Culicoides imicola biting midge vectors of Bluetongue Virus

Mitochondrial DNA. Part B. Resources
Biting midges (Culicoides spp.) are important vectors of several insect borne arboviruses but are underrepresented in terms of availability of high-resolution genomic resources. We assembled and annotated complete mitochondrial genomes for two Culicoides
Khandaker Asif Ahmed, Anjana Karawita, Melissa J. Klein, Luana Fiorella Mincarelli, Barbara Secondini, Giuseppe Satta, Massimo Ancora, Cipriano Foxi, Marco Di Domenico, Michela Quaglia, Maria Goffredo, Alessio Lorusso, Cesare Cammà, Leon Court, Rahul V. Rane, Tom K. Walsh, Prasad N. Paradkar, Debbie Eagles, Gunjan Pandey, Christopher M. Hardy   +19 more
doaj   +1 more source

Assessment of whole genome amplification-induced bias through high-throughput, massively parallel whole genome sequencing

BMC Genomics, 2006
Background Whole genome amplification is an increasingly common technique through which minute amounts of DNA can be multiplied to generate quantities suitable for genetic testing and analysis.
Plant Ramona N, Tartaro Karrie R, Gerstein Mark B, Sarkis Gary J, de Winter Alex, Pinard Robert, Egholm Michael, Rothberg Jonathan M, Leamon John H   +8 more
doaj   +1 more source

Whole Genome Sequencing in Hypoplastic Left Heart Syndrome

Journal of Cardiovascular Development and Disease, 2022
Hypoplastic left heart syndrome (HLHS) is a genetically complex disorder. Whole genome sequencing enables comprehensive scrutiny of single nucleotide variants and small insertions/deletions, within both coding and regulatory regions of the genome ...
Jeanne L. Theis, Timothy M. Olson
doaj   +1 more source

Genomic Characterization of a Wild-Type Bovine alphaherpesvirus 1 (BoAHV-1) Strain Isolated in an Outbreak in Central Italy

Viruses
Bovine alphaherpesvirus-1 (BoAHV-1) infection is common in cattle worldwide. However, information on the spread of BoAHV-1-circulating strains in Italy remains limited.
Stefano Petrini, Valentina Curini, Cecilia Righi, Cesare Cammà, Valeria Di Lollo, Elena Tinelli, Luana Fiorella Mincarelli, Elisabetta Rossi, Giulia Costantino, Barbara Secondini, Silvia Pirani, Monica Giammarioli, Francesco Feliziani   +12 more
doaj   +1 more source

Description of mpox reinfection by whole genome sequencing

International Journal of Infectious Diseases, 2023
Several possible mpox reinfections have been reported, however, the debate on whether these are confirmed reinfections remains open.A 30-year-old male living with HIV and a history of single-dose mpox vaccination, first diagnosed with mpox in September ...
Javier Martínez-Sanz, Manuel Ponce-Alonso, Laura Martínez-García, Víctor de la Cueva, Leticia Olavarrieta, Laura Montero, María Jesús Pérez-Elías, Juan Carlos Galán   +7 more
doaj   +1 more source

Whole genome sequencing of breast cancer [PDF]

APMIS, 2019
Breast cancer was the first to take advantage of targeted therapy using endocrine therapy, and for up to 20% of all breast cancer patients a further significant improvement has been obtained by HER2‐targeted therapy. Greater insight in precision medicine is to some extent driven by technical and computational progress, with the first wave of a true ...
Rossing, Maria, Sørensen, Claus Storgaard, Ejlertsen, Bent, Nielsen, Finn Cilius   +3 more
openaire   +4 more sources

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source