In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
A genome-wide case-only test for the detection of digenic inheritance in human exomes [PDF]
, 2020 Gaspard Kerner +8 more
openalex +1 more source
Journal of Pure and Applied Microbiology, 2018 Enteric fever has emerged as an important infectious disease in the early 19th century. This study is carried out in search of an accurate diagnostic method enabling direct observation of antibody binding to antigen profiles, avoiding problems with non-
K. Sharanya +3 more
doaj +1 more source
Guru pembelajar modul paket keahlian analis kesehatan SMK kelompok kompetensi D: pemeriksaan batu ginjal, pembelajaran yang mendidik. [PDF]
, 2016 Modul ini menyajikan pembuatan media padat/ solid media sesuai fungsinya, mikologi, pemeriksaan hitung jumlah sel darah merah, pemeriksaan bilirubin dan keton urin, pemeriksaan narkotika urin dan pemeriksaan imunoserologi pada berbagai ...
Aini, Qurrata, Kusumawati, Budi
core
Modeling Costs and Life-Years Gained by Population-Wide Next-Generation Sequencing or Single-Gene Testing in Nonsquamous Non–Small-Cell Lung Cancer in the United States [PDF]
, 2023 Christopher A. Lemmon +3 more
openalex +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
APPLICATION OF NEURAL NETWORKS ON BLOOD SERUM IMAGE FOR EARLY DETECTION OF TYPHUS
Indonesian Journal of Tropical and Infectious Disease, 2013 Background: Typhus is a disease caused by Salmonella typhi, Salmonella paratyphi A Salmonella parathypi B, dan Salmonella paratyphi C bacteria that attacks digestive tract and caused infection in small intestine.
Betty Purnamasari +2 more
doaj +1 more source
Genome-wide multimediator analyses using the generalized Berk–Jones statistics with the composite test [PDF]
, 2023 En‐Yu Lai, Yen‐Tsung Huang
openalex +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source