Results 81 to 90 of about 4,470 (211)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

A comparative study of Widal test with blood culture in the diagnosis of typhoid fever in febrile patients. [PDF]

BMC Res Notes, 2014
Andualem G, Abebe T, Kebede N, Gebre-Selassie S, Mihret A, Alemayehu H.   +5 more
europepmc   +1 more source

Study of the pattern of Widal test in infants and children. I. Pattern of Widal test among apparently normal infants and children.

The Gazette of the Egyptian Paediatric Association, 1976
690 apparently normal infants and children from Assiut-Upper Egypt--were submitted to Widal test. They were 0-15 years old, of both sexes (382 males and 308 females) and from both the urban and rural localities (433 and 257 respectively). --The frequency of single agglutinin titers is discussed.
F, Hassanein, H M, Hammam, F, El-Behairy, F M, Mostafa, F M, Allam, M, El-Rehaiwy   +5 more
openaire   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Comparison of Diagnostic Accuracy in Enteric Fever: The Widal Test, Advantage Typhi, and Typhiwell IgM ELISA Against the Gold Standard Blood Culture. [PDF]

Cureus
Hajira SN, Giriyapur Siddappa R, Pasha Sa R, Parveen A, Suresh Kumar Yadav R, Yoganand R.   +5 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

False positive results in the Widal test in adults immunized with the Commirnaty (Pfizer-BioNtech) and BBIBP-CorV (Sinopharm) vaccines against COVID-19. [PDF]

Front Med (Lausanne)
Moya-Salazar J, Ciprian LY, Rojas-Zumaran V, Moya-Salazar B, Goicochea-Palomino EA, Contreras-Pulache H.   +5 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Evaluating alternatives to the Widal test for typhoid fever diagnosis in developing countries: A targeted literature review. [PDF]

J Public Health Afr
Tegene BA, Eshetie MT.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source