Results 191 to 200 of about 11,949,539 (223)

Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape

Advanced Science, EarlyView.
Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim, Minju Lee, Yiming Wang, Eunjin Choi, Ji Sun Park, Kyungmin Park, Hayoung Jeon, Donghyun Kim, Donghyun Lee, Yeeun Lee, Kee‐Pyo Kim, Eunha Kim, Heebeom Koo   +12 more
wiley   +1 more source

Cervical spinal tuberculosis: Consistent imaging clues for early recognition from a case series. [PDF]

Surg Neurol Int
Negoro AP, Setiawati R.
europepmc   +1 more source

Programmable Sequential 4D Actuation in Multistable Kirigami Metamaterials

Advanced Science, EarlyView.
This study presents a modular kirigami metamaterial framework enabling programmable multistability and sequential 4D actuation. By coupling geometry‐controlled multistability with material‐dependent recovery kinetics, spatiotemporal deformation can be precisely programmed.
Eui‐Hyun Kim, Minsung Kim, Hyunsik Yoon, Keun Park   +3 more
wiley   +1 more source

Equity in medical school interviews: a cross-sectional analysis of school type, gender, and widening participation status. [PDF]

BMC Med Educ
Moorjani U, Brown CA, Bonomi L, Sam AH, Khan SA.   +4 more
europepmc   +1 more source

Synergistic Grain Boundary and Phonon Engineering Enables Ultrahigh Thermoelectric Performance in Mg3(Sb, Bi)2‐Based Materials

Advanced Science, EarlyView.
Ta encapsulated melting and Cu doping synergistically engineer grain boundaries and phonon scattering in Mg3(Sb,Bi)2, enabling single‐crystal‐like carrier transport and high thermoelectric performance. ABSTRACT Thermoelectric Mg3(Sb, Bi)2 has emerged as a rising star in virtue of its promising thermoelectric performance and abundant constituent ...
Jingdan Lei, Kai Xu, Kunpeng Zhao, Junzhuo Zhou, Haotian Gao, Yifan Yuan, Tian‐Ran Wei, Min Zhu, Qihao Zhang, Franck Gascoin, Xun Shi   +10 more
wiley   +1 more source

Foraminal widening indicating a spinal nerve tumor in the saber-tooth cat <i>Smilodon fatalis</i> from Rancho La Brea. [PDF]

Front Vet Sci
Schmökel H, Del Chicca F, Hagen Argudin Pina R.   +2 more
europepmc   +1 more source

Tau Aggregate Imaging and Transcriptomics of Alzheimer's Disease Brain at Different Stages of Disease

Advanced Science, EarlyView.
The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English, Dorothea Böken, Matthew W. Cotton, Matthew R. Cheetham, Johanna S. Jackson, Georg Meisl, John S. H. Danial, Paul M. Matthews, Nurun N. Fancy, David Klenerman   +9 more
wiley   +1 more source

Axial variation in conduit dimensions in angiosperm leaves and conifer needles - a review. [PDF]

Front Plant Sci
Gebauer R.
europepmc   +1 more source

The Ethics of Extending Life: Longevity Medicine and Health Inequity. [PDF]

J Med Internet Res
Congdon J.
europepmc   +1 more source

The power of webinars: expanding diverse female representation and role models in surgery. [PDF]

BMC Med Educ
Prayle M, Seddon I, Wallace H.
europepmc   +1 more source