Results 161 to 170 of about 2,948,697 (307)

Wild cereal harvesting ca. 14,000 years ago at Jeftelik (Western Syria). [PDF]

PLoS One
Abdo K, Palomo Pérez A, Anderson PC, Mazzucco N, Haïdar-Boustani M, Teira LC, Ibáñez-Estévez JJ.   +6 more
europepmc   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Wild Backyards

, 2007
Be delighted with the digital stories of 'wild' backyards in Queensland.
Klaebe, Helen G., Burgess, Jean E.
core  

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Dichloroacetate Improves Animal Survival, Growth, Neuromuscular Activity, Mitochondrial Stress and Physiology, and Elevated Lactate in C. elegans pdha-1 and dld-1 RNAi Models of Pyruvate Dehydrogenase Complex Deficiency (PDCD). [PDF]

J Inherit Metab Dis
Remes C, Mathew ND, Miranda V, Haroon S, O'Hara T, Anderson VE, Lavorato M, Keith K, Xiao R, Nakamaru-Ogiso E, Falk MJ.   +10 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

WILD M7A M7S Bedienungsanleitung [PDF]

, 1984
Wild, Heerbrugg
core   +1 more source

Wild, Marie [?] an Gisela Grimm (1 Brief)

WILD, MARIE [?] AN GISELA GRIMM (1 BRIEF) Wild, Marie [?] an Gisela Grimm (1 Brief) (Br5785) Brief 5785 ...
Grimm, Gisela, Wild, Marie
core   +1 more source

Elevation-associated variation in bumble bee venom composition is not retained under common-garden conditions. [PDF]

Proc Biol Sci
Barkan NP, Christman ME, Verble KM, Heraghty SD, Campion C, Keaveny EC, Waybright SA, Stamper GM, Lozier JD, Dillon ME, Strange JP.   +10 more
europepmc   +1 more source