Results 51 to 60 of about 4,374,159 (298)

Reliable Eigenspectra for New Generation Surveys [PDF]

, 2009
We present a novel technique to overcome the limitations of the applicability of Principal Component Analysis to typical real-life data sets, especially astronomical spectra.
Alexander S. Szalay, Balogh, Budavári, Budavári, Ching-Wa Yip, Connolly, Connolly, Connolly, Dobos, Everson, Francis, Glazebrook, Huber, Karhunen, Le Fèvre, Li, Loève, László Dobos, Maronna, Maronna, McCracken, Tamás Budavári, Vivienne Wild, Wild, Wild, Wild, Yip, Yip   +27 more
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Positioning for conceptual development using latent semantic analysis [PDF]

, 2009
With increasing opportunities to learn online, the problem of positioning learners in an educational network of content offers new possibilities for the utilisation of geometry-based natural language processing techniques.
Burek, Gaston, Hoisl, Bernhard, Wild, Fridolin   +2 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The growth of plants containing pyrrolizidine alkaloids (PAs) in plots cultivated with medicinal aromatic plants (MAPs) and in their natural wild habitats in Kosovo

Acta Agriculturae Slovenica
Thousands of plant species worldwide produce about 600 different pyrrolizidine alkaloids (PAs), which are known to cause disease in humans and animals. The plants known for their  PAs content were investigated in 70 plots cultivated with 19 MAPs species ...
Fadil MILLAKU, Agim RYSHA, Naim BERISHA
doaj   +1 more source

Assessing consumer acceptance of organic sausage products without curing agents [PDF]

, 2007
This paper presents and comments the results of sales experiments on newly developed organic meat products. The main goal of a research study was to examine the issue of consumer acceptance of organic sausage products with no curing agents.
Hamm, Ulrich, Wild, Sandra
core  

Wild gender [PDF]

, 2019
This chapter invokes some threads in Strathern’s thinking to reframe some of the key questions that animate trans and queer studies today: How did gender, as a category, become a productive threshold capable of attuning abstract sensibilities towards sets of relations and associations not hitherto understood to be attuned?
openaire   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Delving into the Aftermath of a Disease-Associated Near-Extinction Event: A Five-Year Study of a Serpentovirus (Nidovirus) in a Critically Endangered Turtle Population

Viruses
Bellinger River virus (BRV) is a serpentovirus (nidovirus) that was likely responsible for the catastrophic mortality of the Australian freshwater turtle Myuchelys georgesi in February 2015.
Kate Parrish, Peter Kirkland, Paul Horwood, Bruce Chessman, Shane Ruming, Gerry McGilvray, Karrie Rose, Jane Hall, Lee Skerratt   +8 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source