Results 51 to 60 of about 2,948,697 (307)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Research Note. Trichinella spiralis parasitizing Puma concolor: first record in wildlife in Chile

Helminthologia, 2015
The genus Trichinella is widespread in all continents but Antarctica. The only way to identify the species/genotypes is through molecular analyses. In Chile, only one study has reported Trichinella larvae in a cougar, but the species of Trichinella was ...
Landaeta-Aqueveque C., Krivokapich S., Gatti G. M., Prous C. Gonzalez, Rivera-Bückle V., Martín N., González-Acuña D., Sandoval D.   +7 more
doaj   +1 more source

Knowledge, Attitudes and Practices Regarding Sylvatic Rabies among High-Risk Households in Ceará State, Brazil

Tropical Medicine and Infectious Disease, 2021
Rabies transmitted by sylvatic populations has become an increasing concern in Brazil. A total of 113 participants with a history of contact with sylvatic populations were interviewed in 27 municipalities of Ceará State in northeast Brazil ...
Naylê Francelino Holanda Duarte, Patrícia Pereira Lima Barbosa, Danielle Bastos Araujo, Silvana Regina Favoretto, Phyllis Catharina Romijn, Raphael William Pontes Neres, Raquel Holanda Varela, Walber Feijó de Oliveira, Carlos Henrique Alencar, Jorg Heukelbach   +9 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Getting to the Meat of It: The Effects of a Captive Diet upon the Skull Morphology of the Lion and Tiger

Animals, 2023
Zoo animals are crucial for conserving and potentially re-introducing species to the wild, yet it is known that the morphology of captive animals differs from that of wild animals.
David M. Cooper, Nobuyuki Yamaguchi, David W. Macdonald, Bruce D. Patterson, Galina P. Salkina, Viktor G. Yudin, Andrew J. Dugmore, Andrew C. Kitchener   +7 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Gonadal Maturation and Spawning of Barred Loach (Nemacheilus fasciatus) Induced by Topical Gill Hormone Application

Jurnal Medik Veteriner
Barred loach Nemacheilus fasciatus are unable to reproduce naturally in captivity due to the lack of environmental cues and gonadal maturation occurs slower than in the wild.
Darmawan Setia Budi, Buyung Raga Ardiyan, Dani Bagus Rahmawan, Josie South, Arif Habib Fasya, Akhmad Taufiq Mukti   +5 more
doaj   +1 more source

Comparative gonadogenesis and hormonal induction of spawning of cultured and wild mediterranean amberjack (Seriola dumerili, Risso 1810)

Scientia Marina, 2001
The histological characteristics of wild and cultured Mediterranean amberjack gonads were studied during the first four years of their life cycle. No differences were found in the gonad development of both wild and captive males and females during the ...
V. Kozul, B. Skaramuca, B. Glamuzina, N. Glavic, P. Tutman   +4 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Linepithema cerradense Wild

, 2007
cerradense Wild 2007. Canindeyú, Central, Cordillera (ALWC, BMNH, CASC, IFML, INBP, LACM, MCZC, MHNG MZSP, NHMB, UCDC, USNM). Literature records: Canindeyú, Central, Cordillera (Wild 2007).Published as part of Wild, A.
Wild, A. L.
core   +1 more source