Results 111 to 120 of about 1,824,485 (310)

No naturally occurring blood group antibodies were detected in the crossmatching of 25 giant pandas

open access: yesScientific Reports
The giant panda (Ailuropoda melanoleuca) is a vulnerable species of ursid, endemic to China. With over eight million years of evolution, it is considered a living fossil.
Yonghua Yin   +19 more
doaj   +1 more source

Evaluation of Different Decellularization Protocols for Obtaining and Characterizing Canine Cardiac Extracellular Matrix

open access: yesBiomedicines
Cardiovascular diseases are considered the leading cause of mortality globally; even with low mortality in dogs, such diseases are described in the same way in companion animals and humans.
Izabela Gabriela Rodrigues da Silva   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Journey of the Default Mode Network: Development, Function, and Impact on Mental Health

open access: yesBiology
The Default Mode Network has been extensively studied in recent decades due to its central role in higher cognitive processes and its relevance for understanding mental disorders.
Felipe Rici Azarias   +4 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

From Gettysburg to Townsville, Australia and Back

open access: yes, 2016
I studied abroad in Townsville, AU in the Fall 2014 and had the semester of my life. I am biology major, who has always wanted to pursue a career with animals and I got to run hands on experiments at James Cook University.
Ehrhardt, Caroline A.
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

From Cartilage to Matrix: Protocols for the Decellularization of Porcine Auricular Cartilage

open access: yesBioengineering
The shortage of tissues and damaged organs led to the development of tissue engineering. Biological scaffolds, created from the extracellular matrix (ECM) of organs and tissues, have emerged as a promising solution for transplants.
Ana Caroline dos Santos   +9 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Butterflies, Magic Carpets, and Scary Wild Animals: An Intervention with a Young Gymnast [PDF]

open access: yes, 2016
This article presents a reflective case example of a sport psychology consultation carried out with a 9-year-old gymnast during the final year of the consultant’s training to become a British Psychological Society (BPS) chartered sport psychologist ...
Howells, Karen
core  

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