Results 121 to 130 of about 1,837,425 (310)
Painted Ferocity: The Social Behaviors of African Wild Dogs, Threats to Survival, and Resulting Conservation Initiatives [PDF]
, 2018 African Wild Dogs (Lycaon pictus) are an endangered species of canid from Sub-Saharan Africa. They are very social communal hunters, and are capable of chasing down prey for long stretches of time. Wild dogs benefit a savannah ecosystem by regulating the
Valdes, Alexis
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
The Journey of the Default Mode Network: Development, Function, and Impact on Mental Health
BiologyThe Default Mode Network has been extensively studied in recent decades due to its central role in higher cognitive processes and its relevance for understanding mental disorders.
Felipe Rici Azarias +4 more
doaj +1 more source
Bio-logging and animal welfare: practical refinements [PDF]
, 2004 Although bio-logging can benefit both science and animal welfare, its application involves procedures that can cause animals pain, suffering and distress.
Penny Hawkins
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
From Cartilage to Matrix: Protocols for the Decellularization of Porcine Auricular Cartilage
BioengineeringThe shortage of tissues and damaged organs led to the development of tissue engineering. Biological scaffolds, created from the extracellular matrix (ECM) of organs and tissues, have emerged as a promising solution for transplants.
Ana Caroline dos Santos +9 more
doaj +1 more source
Features of reproduction and assisted reproduction in the white (Ceratotherium simum) and black (Diceros bicornis) rhinoceros [PDF]
, 2015 Despite the worldwide increase of rhinoceros calf numbers, the growth of the population of white and black rhinoceros is slowing down mainly due to anthropogenic causes, such as poaching and habitat loss.
Govaere, Jan +3 more
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FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Serp2, an inhibitor of the interleukin-1beta-converting enzyme, is critical in the pathobiology of myxoma virus [PDF]
, 1998 Recently, myxoma virus was shown to encode an additional member of the serpin superfamily. The viral gene, called serp2, was cloned, and the Serp2 protein was shown to specifically bind to interleukin-1beta (IL-1beta)-converting enzyme (ICE), thus ...
Messud-Petit, Frédérique +6 more
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