From Payload‐First Toward Dual‐Mechanism Antibody–Drug Conjugates
Conjugation converts potent antibodies into underexposed carriers. This perspective defines the antibody exposure deficit and maps a mechanism‐first design space from payload‐first to antibody‐first ADC architectures, integrating DAR, linker chemistry, and Fc engineering to guide rational design of constructs that balance targeted cytotoxicity with ...
Xavier Pivot +3 more
wiley +1 more source
Molecular and serological diagnosis of Toxoplasma gondii infection in wild animals in the Pantanal in Brazil. [PDF]
Dahroug MAA +10 more
europepmc +1 more source
Sustainable Plant‐Based Water Repellent Coatings Using Hydrophobic Pine and Palm Pollen
A novel formulation strategy for creating superhydrophobic coatings using plant‐derived waxes and chemically treated pine and palm pollen. By employing acid modification, the hydrophobicity of the pollen surface is enhanced, resulting in water contact angles exceeding 150°.
Brenda Resendiz‐Diaz +2 more
wiley +1 more source
Detection of IgG antibody against the porcine norovirus GII.11 in human, domestic and wild animals. [PDF]
Xu J +10 more
europepmc +1 more source
Conformable Ferrimagnetic Tattoo Electrodes for Plant Electrophysiology
The newly developed ferrimagnetic tattoo electrode is capable of measuring plant electrophysiological activity outside the Faraday cage. Its ability to adhere without damaging the plant tissue allows long‐term recordings. This premise opens new avenues for in‐field monitoring of plant health through electrophysiology.
Arianna Melis +7 more
wiley +1 more source
Epidemiological Study of Cryptococcus gattii Complex Infection in Domestic and Wild Animals in Oregon. [PDF]
Ballard S +5 more
europepmc +1 more source
A collagen‐based gut‐on‐chip model replicates the intestinal extracellular matrix, supporting villi‐like structures, tight junctions, and mucin production. This biomimetic platform enables rapid epithelial differentiation and functional barrier formation.
Fernanda López García +4 more
wiley +1 more source
Identification of a putative new virus from the <i>Jingmenvirus</i> group in ticks from wild animals in Brazil. [PDF]
Geraldini DB +14 more
europepmc +1 more source
Multimodal Engagement Assessment in Children During Invented Story Paradigm With a Social Robot
A multimodal framework is proposed to assess children's engagement during storytelling interactions with a social robot. Gaze, physiological, and behavioral data are combined and validated against observer ratings. An automated gaze‐labeling strategy is introduced, and supervised classifiers achieve high accuracy. The study supports scalable engagement
Laura Fiorini +7 more
wiley +1 more source
Crimean-Congo haemorrhagic fever virus in ticks, domestic, and wild animals. [PDF]
Celina SS +3 more
europepmc +1 more source

