Results 111 to 120 of about 1,837,425 (310)
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Disruption of the mouse MRF4 gene identifies multiple waves of myogenesis in the myotome [PDF]
, 1995 MRF4 (herculin/Myf-6) is one of the four member MyoD family of transcription factors identified by their ability to enforce skeletal muscle differentiation upon a wide variety of nonmuscle cell types.
Miner, Jeffrey H. +5 more
core
Antibodies aggravate the development of ischemic heart failure [PDF]
, 2018 Heart-specific antibodies have been widely associated with myocardial infarction (MI). However, it remains unclear whether autoantibodies mediate disease progression or are a byproduct of cardiac injury. To disambiguate the role of immunoglobulins in MI,
Frantz, Stefan +6 more
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Uterine Involution and Reproductive Performance in Dairy Cows with Metabolic Diseases
Animals, 2019 The aim of this study was to investigate the effects of metabolic diseases on uterine involution and reproductive performance during the postpartum period.
Renan Braga Paiano +2 more
doaj +1 more source
Exotic and invasive terrestrial and freshwater animal species in the Dutch Caribbean [PDF]
An overview of 72 invasive animals of the terrestrial and freshwater environments of the Dutch Caribbean, eleven of which are no longer present. All invasive animals that are principally agricultural pests and or animal and plant diseases (46 species ...
Buurt, G., van, Debrot, A.O.
core +1 more source
High-Speed Rail and Equine Issues [PDF]
, 2015 Community concerns have been raised about the possible negative impacts of high-speed rail (HSR) service on equestrian areas. Although much is known about the impact of aircraft noise on wild and domestic animals, relatively little information is ...
Haas, Peter J, Scrivener, Allie
core +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
No naturally occurring blood group antibodies were detected in the crossmatching of 25 giant pandas
Scientific ReportsThe giant panda (Ailuropoda melanoleuca) is a vulnerable species of ursid, endemic to China. With over eight million years of evolution, it is considered a living fossil.
Yonghua Yin +19 more
doaj +1 more source
BiomedicinesCardiovascular diseases are considered the leading cause of mortality globally; even with low mortality in dogs, such diseases are described in the same way in companion animals and humans.
Izabela Gabriela Rodrigues da Silva +4 more
doaj +1 more source