Results 91 to 100 of about 874,930 (242)

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum, Milli McMenamin, Tessa Khoo, John M. Edwin, Prathibha Jose, Liam A. O’Callaghan   +5 more
wiley   +1 more source

Brain size/body weight in the dingo (Canis dingo): Comparisons with domestic and wild canids

, 2017
Smith, BP ORCiD: 0000-0002-0873-3917Endocranial volume was measured in a large sample (n=128) of free ranging dingoes (Canis dingo) where body size was known.
Bradley P. Smith, Henneberg, M., M Henneberg (9886355), Teghan A. Lucas, Lucas, T., Henneberg, M, Maciej Henneberg, Bradley Smith (9836054), Norris, RM, RM Norris (9886352), Norris, R., Smith, BP, TA Lucas (9886349), Smith, B., Lucas, TA, Rachel M. Norris   +15 more
core   +1 more source

Labeling Strategies for Monitoring Cytoskeleton Dynamics in Cultured Epithelial Cells

Cytoskeleton, EarlyView.
ABSTRACT Collective cell migration relies on coordinated cytoskeletal remodeling, yet the impact of live‐cell actin filament probes on these dynamics remains poorly characterized. Here, we systematically compared the performance and cellular effects of fluorogenic jasplakinolide‐based probes, SiR‐actin and SiR‐XActin, with the genetically encoded ...
Victoria Levario‐Diaz, Lakshmi Nyapathi‐Gopinath, Jonah Luka Voigt, Katharina Weber, Marlene Maager, Veselin Nasufovic, Elisabetta Ada Cavalcanti‐Adam   +6 more
wiley   +1 more source

The status of wild canids (Canidae, Carnivora) in Vietnam

Journal of Threatened Taxa, 2019
Four species of wild canids are documented as occurring in Vietnam: Dhole Cuon alpinus, Eurasian Golden Jackal Canis aureus, Red Fox Vulpes vulpes and Raccoon Dog Nyctereutes procyonoides.  Except for Dhole, all species are widely distributed globally and are listed as Least Concern on the IUCN Red List of Threatened Species.
Daniel Willcox, Tran Van Bang, Robert Timmins, Ben Rawson, Nguyen Truong Son, An Nguyen, Barney Long, Le Trong Trai, Hoang Minh Duc, Alexei Abramov, Michael Hoffmann   +10 more
openaire   +1 more source

Membrane lipid metabolism as a regulatory frontier in neural crest biology: Roles for sphingolipids, cholesterol, and lipid rafts

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini, Mallorie P. Jenne, Michael L. Piacentino   +2 more
wiley   +1 more source

Canine Rabies Ecology in Southern Africa

Emerging Infectious Diseases, 2005
Rabies is a widespread disease in African domestic dogs and certain wild canine populations. Canine rabies became established in Africa during the 20th century, coinciding with ecologic changes that favored its emergence in canids. I present a conceptual
John Bingham
doaj   +1 more source

From patterns to predictions: a framework for the spatial epidemiology of wildlife diseases

Ecography, EarlyView.
Wildlife diseases pose a significant threat to biodiversity conservation, public health, and livestock. Spatial epidemiology provides a robust framework to understand disease dynamics and guide policy and management. However, the rapid proliferation of spatial methods has largely occurred in isolation across disciplines, leaving the field without a ...
Cesar Herraiz, Pelayo Acevedo
wiley   +1 more source

Scaling of the corpus callosum in wild and domestic canids: Insights into the domesticated brain. [PDF]

, 2019
All domesticated mammals exhibit marked reductions in overall brain size, however, it is unknown whether the corpus callosum, an integral white matter fiber pathway for interhemispheric cortical communication, is affected by domestication differentially ...
Rusbridge, Clare, Haas, Jordan, Uddin, Ashraf, Tang, Cheuk, Raghanti, Mary Ann, Spocter, Muhammad A, Wong, Edmund, Ng, Johnny C, Sherwood, Chet C, Wicinski, Bridget, Hof, Patrick R, Wang, Victoria X, Dunn, Rachel, Bitterman, Kathleen, Manger, Paul R, Jovanovik, Jelena   +15 more
core   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Let's Talk About Bone Cylinders. Taphonomy of Carnivores and Humans

International Journal of Osteoarchaeology, EarlyView.
ABSTRACTBone cylinders are a distinctive structure predominantly produced by durophagous carnivoran species during the consumption of long bones, in which the diaphyseal canal remains intact while both epiphyses are removed or consumed. This study evaluates the significance of this morphology, traditionally attributed to extant and extinct hyena ...
Darío Herranz‐Rodrigo
wiley   +1 more source