Results 101 to 110 of about 952,049 (324)

Quantitative trait loci conferring grain mineral nutrient concentrations in durum wheat 3 wild emmer wheat RIL population [PDF]

open access: yes, 2009
Mineral nutrient malnutrition, and particularly deficiency in zinc and iron, afflicts over 3 billion people worldwide. Wild emmer wheat, Triticum turgidum ssp. dicoccoides, genepool harbors a rich allelic repertoire for mineral nutrients in the grain.
A Blanco   +81 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Diverse biological effects of glycosyltransferase genes from Tartary buckwheat [PDF]

open access: yes, 2019
Background: Tartary buckwheat (Fagopyrum tataricum) is an edible cereal crop whose sprouts have been marketed and commercialized for their higher levels of anti-oxidants, including rutin and anthocyanin. UDP-glucose flavonoid glycosyltransferases (UFGTs)
Chen, Hui   +12 more
core   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

A comparison of the wild food plant use knowledge of ethnic minorities in Naban River Watershed National Nature Reserve, Yunnan, SW China

open access: yesJournal of Ethnobiology and Ethnomedicine, 2012
Background Wild food plants (WFPs) contribute to the nutrition, economy and even cultural identity of people in many parts of the world. Different factors determine the preference and use of WFPs such as abundance, availability, cultural preference ...
Ghorbani Abdolbaset   +2 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

African botanical heritage for new crop development [PDF]

open access: yes, 2008
The African continent is rather poor in plant biodiversity when compared to other continents on and around the equator. Nevertheless, lots of useful plant species have been domesticated from Sub-Sahara Africa material.
Termote, Céline, Van Damme, Patrick
core   +3 more sources

Food from the Wild—Roles and Values of Wild Edible Plants and Fungi

open access: yesFoods
Humans have used a multitude of wild species of plants, fungi, and animals for food and medicinal purposes [...]
Luis Catarino   +2 more
openaire   +5 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Sustained by First Nations: European newcomers' use of Indigenous plant foods in temperate North America

open access: yesActa Societatis Botanicorum Poloniae, 2012
Indigenous Peoples of North America have collectively used approximately 1800 different native species of plants, algae, lichens and fungi as food.
Nancy J. Turner, Patrick von Aderkas
doaj   +1 more source

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