Results 41 to 50 of about 325,483 (256)
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
The First Report of Rhipicephalus (Boophilus) kohlsi (Hoog¬straal and Kaiser 1960) from Wild Goats (Capra hircus aega¬grus) in Iran [PDF]
Iranian Journal of Parasitology, 2007 Background: Studies concerning ticks were of interest to evaluate the distribution and composition of species affecting live¬stock, thus it was a main step in our knowledge of the pathogens that they may transmit by tick.
S Rahbari +1 more
doaj +1 more source
Veterinary World, 2013 Aim: Chital and sambar are the common wild small herbivores, which are vulnerable to poaching for their meat. Many times poachers claim the wild meat to be that of goat or sheep. Hence, authentic evidences are required to stop such wildlife crime.
E. Joseph +5 more
doaj +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Habitat suitability modeling for wild goat (Capra aegagrus) in a mountainous arid area, central Iran
Caspian Journal of Environmental Sciences, 2013 Wild goat (Capra aegagrus) is one of the most prominent mountain mammals dispersed in many habitats in Iran. However, few studies on the relationship between this species and its habitat have been conducted.
Sarhangzadeh, J. +4 more
doaj
Genetic origin of goat populations in Oman revealed by mitochondrial DNA analysis.
PLoS ONE, 2017 The Sultanate of Oman has a complex mosaic of livestock species and production systems, but the genetic diversity, demographic history or origins of these Omani animals has not been expensively studied. Goats might constitute one of the most abundant and
Nasser Ali Al-Araimi +5 more
doaj +1 more source
Journal of Agricultural Sciences, 2009 A comprehensive knowledge of the ecology and associating plant species of wheat progenitors is important for plant scientists. This study was designed as a case study to focus on the relation between 5 wild relatives of wheat Aegilops spp. L.
Alptekin Karagöz +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source