Results 21 to 30 of about 76,572 (264)

A fully phased octoploid strawberry genome reveals the evolutionary dynamism of centromeric satellites

open access: yesGenome Biology
We systematically examine the application of different phasing strategies to decrypt strawberry genome organization and produce a fully phased and accurate reference genome for Fragaria x ananassa cv. “EA78” (2n = 8x = 56).
Xin Jin   +5 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Plastome evolution and phylogenomics of Glycine (Leguminosae: Papilionoideae)

open access: yesBMC Plant Biology
The genus Glycine Willd. is economically important due to the soybean, a major global crop for oil and protein. However, comprehensive phylogenetic studies of this genus are lacking, and plastome evolution remains poorly understood.
Kai-Lun An   +11 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Chromosome-level reference genome assembly for the protected resource plant, Zenia insignis

open access: yesScientific Data
Zenia insignis Chun, from the subfamily Dialioideae of the family Fabaceae, is a tree species of significant economic and ecological values. It is a near threatened species as per the IUCN Red List.
Si-Yun Chen   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Unprecedented variation pattern of plastid genomes and the potential role in adaptive evolution in Poales

open access: yesBMC Biology
Background The plastid is the photosynthetic organelle in plant cell, and the plastid genomes (plastomes) are generally conserved in evolution. As one of the most economically and ecologically important order of angiosperms, Poales was previously ...
Hong Wu, De-Zhu Li, Peng-Fei Ma
doaj   +1 more source

Genetic Diversity and Utilization of Cultivated Eggplant Germplasm in Varietal Improvement

open access: yesPlants, 2021
Eggplant is the fifth economically most important vegetable in the Solanaceae family after tomato, potato, chili, and tobacco. Apart from the well-cultivated brinjal or aubergine eggplant (Solanum melongena L.), two other underutilized eggplant species ...
Yusuff Oladosu   +7 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Specimen Identification Through Multilocus Species Tree Constructed From Single‐Copy Orthologs (SCOs): A Case Study in Cymbidium Subgenus Jensoa

open access: yesEcology and Evolution
Standard barcodes and ultra‐barcode encounter significant challenges when delimiting and discriminating closely related species characterized by deep coalescence, hybrid speciation, gene flow, or low sequence variation.
Zheng‐Shan He   +4 more
doaj   +1 more source

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