Results 21 to 30 of about 1,079,692 (209)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Crop wild relatives in Natura 2000 Network [PDF]

, 2021
This document presents the results of analyses to ascertain the potential of the Natura 2000 network to conserve crop wild relatives (CWR). We obtained distribution data of European priority CWR from large international biodiversity databases and ...
Kell, Shelagh, Gaisberger, Hannes, Iriondo, Jose Maria, Maxted, Nigel, Rubio Teso, Maria Luisa, Lara-Romero, Carlos, Álvarez Muñiz, Clara, Magos Brehm, Joana   +7 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Crop wild relatives: Reprinted from Geneflow 2006

, 2019
Crop wild relatives include crop ancestors as well as other species more or less closely related to crops. They are a critical source of genes for resistance to diseases, pests and stresses such as drought and extreme temperatures.
Crop Wild Relatives
core   +1 more source

Specimen Identification Through Multilocus Species Tree Constructed From Single‐Copy Orthologs (SCOs): A Case Study in Cymbidium Subgenus Jensoa

Ecology and Evolution
Standard barcodes and ultra‐barcode encounter significant challenges when delimiting and discriminating closely related species characterized by deep coalescence, hybrid speciation, gene flow, or low sequence variation.
Zheng‐Shan He, Ji‐Xiong Yang, Jia‐Lin Huang, De‐Zhu Li, Jun‐Bo Yang   +4 more
doaj   +1 more source

Positive selection and relaxed purifying selection contribute to rapid evolution of male-biased genes in a dioecious flowering plant

eLife
Sex-biased genes offer insights into the evolution of sexual dimorphism. Sex-biased genes, especially those with male bias, show elevated evolutionary rates of protein sequences driven by positive selection and relaxed purifying selection in animals ...
Lei Zhao, Wei Zhou, Jun He, De-Zhu Li, Hong-Tao Li   +4 more
doaj   +1 more source

North American Wild Relatives of Grain Crops [PDF]

, 2019
The wild-growing relatives of the grain crops are useful for long-term worldwide crop improvement research. There are neglected examples that should be accessioned as living seeds in gene banks.
Brenner, David, Harold E. Bockelman, Williams, Karen, David M. Brenner, Bockelman, Harold, Karen A. Williams   +5 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Multiple Glacial Refugia and Complex Postglacial Dynamics of Primula sikkimensis (Primuaceae) in the Heterogeneous Qinghai‐Tibet Plateau

Ecology and Evolution
The Qinghai‐Tibet Plateau (QTP) is a global biodiversity hotspot where Quaternary climatic oscillations profoundly shaped the evolution of endemic alpine flora.
Hua‐Ying Sun, Yu‐Ting He, Zhi‐Hua Zeng, Yuan‐Mi Wu, Li Zhong, Qing‐Hong Feng, Hui‐Ying Gong, Xin Wang, Hong Wang, Zhi‐Kun Wu, Wei Zhou   +10 more
doaj   +1 more source