Results 71 to 80 of about 5,730,646 (258)
Parasites of the African painted dog (Lycaon pictus) in captive and wild populations: Implications for conservation [PDF]
, 2011 The African painted dog (Lycaon pictus) is a highly endangered carnivore of sub- Saharan Africa, which in the last century has suffered a population decline of almost 99%. With only 3,000-5,500 animals remaining in the wild it is imperative to understand
Ash, Amanda
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The world's vanishing wild places are vital for saving species [PDF]
, 2016 [Extract] In science, it's rare that a new idea comes along that stops people in their tracks. For ecologists, this has just happened, in a paper that found that species living in wild places have more genetic diversity than the same species living in ...
Laurance, Bill
core +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
A gap analysis methodology for collecting crop genepools: a case study with Phaseolus beans [PDF]
, 2010 Background The wild relatives of crops represent a major source of valuable traits for crop improvement. These resources are threatened by habitat destruction, land use changes, and other factors, requiring their urgent collection and long-term ...
Debouck, D.G. +23 more
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BMC BiologyBackground The plastid is the photosynthetic organelle in plant cell, and the plastid genomes (plastomes) are generally conserved in evolution. As one of the most economically and ecologically important order of angiosperms, Poales was previously ...
Hong Wu, De-Zhu Li, Peng-Fei Ma
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Use made of wild legume relatives in breeding [PDF]
, 2010 Presently vast genetic resources are available for improvement of the main crops used by humans and animals. The ex-situ collections safeguard those resources collected in the past, although not all collections are safe even today as far as personnel and
Upadhyaya, H.D. +2 more
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Population Genetic Approaches to Speciation of Wild Tomatoes with Special Reference to Solanum habrochaites and S. arcanum [PDF]
, 2009 This thesis entails the results of three research projects. These have focused on the influence of diversity, demography and structure in the divergence (i.e. the speciation process) of four wild tomato species.
Merino Méndez, Carlos Gonzalo
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Industrial Crops and ProductsJuglans sigillata is an economically important endemic walnut species in southwest China, renowned for its unique stress adaptation abilities and significantly higher serotonin content than the widely cultivated common walnut (J. regia).
Jing Ling +13 more
doaj +1 more source