Results 31 to 40 of about 262,063 (287)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Deserts of Development: How God Shapes Leaders in the Wilderness [PDF]
, 2010 A wilderness experience in the life of a believer is often a tool used by God to shape him for some leadership position or specific calling. While the desert one is thrust into may be physical in nature or purely psychological, wilderness experiences ...
Dickson, Jeffrey R
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
‘Wild land’: a concept in search of space [PDF]
, 2004 This paper sets out the general background context surrounding the issue of wild land in Scotland. It explores definitions of wild land and related concepts, identifies key issues associated with wild land in Scotland, and explores the question of the ...
Powell, John R +2 more
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Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Wilderness attribute mapping in the United Kingdom [PDF]
, 2002 A wilderness continuum concept can identify the wilder areas of Britain. Geographical Information Systems are used to present information on these areas and solicit public opinion as to which factors are perceived to be important wilderness quality ...
Carver, S., Evans, A.J., Fritz, S.
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A Trip to the Co-op: The Production, Consumption and Salvation of CanadianWilderness [PDF]
, 2009 In this paper, I analyze Mountain Equipment Co-op (MEC) catalogues from1987-2007, in order to examine how they produce wilderness, invite consumption andoffer up their products as a means of salvation for wilderness and for MEC members.My analysis of the
Vander Kloet, Marie
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Connecting the Dots: Linking Sustainable Wild Capture Fisheries Initiatives and Impact Investors [PDF]
, 2016 Wilderness Markets undertook a series of fishery value chain assessments to better understand the opportunities and constraints for private impact capital to flow into wild capture fisheries markets.
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